Center-Authored Papers

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Veatch JR, Lee SM, Fitzgibbon M, Chow I-T, Jesernig B, Schmitt T, Kong YY, Kargl J, Houghton MGA, Thompson JA et al..  2018.  Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma.. The Journal of clinical investigation. 128(4):1563-1568. Abstract
Wang X, Chang W-C, Wong CLW, Colcher D, Sherman M, Ostberg JR, Forman SJ, Riddell SR, Jensen MC.  2011.  A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells.. Blood. 118(5):1255-63. Abstract
Gerhard DS, Clemons PA, Shamji AF, Hon C, Wagner BK, Schreiber SL, Krasnitz A, Sordella R, Sander C, Lowe SW et al..  2016.  Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance.. Molecular cancer research : MCR. Abstract
Warren EH, Fujii N, Akatsuka Y, Chaney CN, Mito JK, Loeb KR, Gooley TA, Brown ML, Koo KKW, Rosinski KV et al..  2010.  Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens.. Blood. 115(19):3869-78. Abstract
Sadelain M, Rivière I, Riddell S.  2017.  Therapeutic T cell engineering.. Nature. 545(7655):423-431. Abstract
Pollack SM, Jones RL, Farrar EA, Lai IP, Lee SM, Cao J, Pillarisetty VG, Hoch BL, Gullett A, Bleakley M et al..  2014.  Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8(+) T cells.. Journal for immunotherapy of cancer. 2(1):36. Abstract
Nauerth M, Weißbrich B, Knall R, Franz T, Dössinger G, Bet J, Paszkiewicz PJ, Pfeifer L, Bunse M, Uckert W et al..  2013.  TCR-Ligand koff Rate Correlates with the Protective Capacity of Antigen-Specific CD8+ T Cells for Adoptive Transfer.. Science translational medicine. 5(192):192ra87. Abstract
Paszkiewicz PJ, Fräßle SP, Srivastava S, Sommermeyer D, Hudecek M, Drexler I, Sadelain M, Liu L, Jensen MC, Riddell SR et al..  2016.  Targeted antibody-mediated depletion of murine CD19 CAR T cells permanently reverses B cell aplasia.. The Journal of clinical investigation. 126(11):4262-4272. Abstract
Menger L, Gouble A, Marzolini MAV, Pachnio A, Bergerhoff K, Henry JY, Smith J, Pule M, Moss P, Riddell SR et al..  2015.  TALEN-mediated genetic inactivation of the glucocorticoid receptor in cytomegalovirus-specific T cells.. Blood. 126(26):2781-2789. Abstract
Pollack SM, He Q, Yearley JH, Emerson R, Vignali M, Zhang Y, Redman MW, Baker KK, Cooper S, Donahue B et al..  2017.  T-cell infiltration and clonality correlate with programmed cell death protein 1 and programmed death-ligand 1 expression in patients with soft tissue sarcomas.. Cancer. Abstract
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Gutman JA, Turtle CJ, Manley TJ, Heimfeld S, Bernstein ID, Riddell SR, Delaney C.  2010.  Single-unit dominance after double-unit umbilical cord blood transplantation coincides with a specific CD8+ T-cell response against the nonengrafted unit.. Blood. 115(4):757-65. Abstract
Graef P, Buchholz VR, Stemberger C, Flossdorf M, Henkel L, Schiemann M, Drexler I, Höfer T, Riddell SR, Busch DH.  2014.  Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells.. Immunity. 41(1):116-26. Abstract
Berger C, Sommermeyer D, Hudecek M, Berger M, Balakrishnan A, Paszkiewicz PJ, Kosasih PL, Rader C, Riddell SR.  2015.  Safety of targeting ROR1 in primates with chimeric antigen receptor-modified T cells.. Cancer immunology research. 3(2):206-16. Abstract
Berger C, Berger M, Hackman RC, Gough M, Elliott C, Jensen MC, Riddell SR.  2009.  Safety and immunologic effects of IL-15 administration in nonhuman primates.. Blood. 114(12):2417-26. Abstract
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Elmacken M, Awasthi A, Ayello J, van de Ven C, Luo W, Liao Y, Riddell S, Cairo M.  2015.  ROR1 expressing neuroblastoma (NB), medulloblastoma (MB), and ewing’s sarcoma (ES) can be effectively targeted with nk cells modified to express an anti ROR1 chimeric antigen receptor (CAR). Cytotherapy. 17(6):S48.
Busch DH, Fräßle SP, Sommermeyer D, Buchholz VR, Riddell SR.  2016.  Role of memory T cell subsets for adoptive immunotherapy.. Seminars in immunology. 28(1):28-34. Abstract
Brown CE, Starr R, Martinez C, Aguilar B, D'Apuzzo M, Todorov I, Shih C-C, Badie B, Hudecek M, Riddell SR et al..  2009.  Recognition and killing of brain tumor stem-like initiating cells by CD8+ cytolytic T cells.. Cancer research. 69(23):8886-93. Abstract
Hudecek M, Lupo-Stanghellini M-T, Kosasih PL, Sommermeyer D, Jensen MC, Rader C, Riddell SR.  2013.  Receptor Affinity and Extracellular Domain Modifications Affect Tumor Recognition by ROR1-Specific Chimeric Antigen Receptor T Cells.. Clinical cancer research : an official journal of the American Association for Cancer Research. 19(12):3153-3164. Abstract
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Berger C, Berger M, Beard BC, Kiem H-P, Gooley TA, Riddell SR.  2013.  Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques.. PloS one. 8(2):e56268. Abstract
Rufener GA, Press OW, Olsen P, Lee SY, Jensen MC, Gopal AK, Pender B, Budde LE, Rossow JK, Green DJ et al..  2016.  Preserved Activity of CD20-Specific Chimeric Antigen Receptor-Expressing T Cells in the Presence of Rituximab.. Cancer immunology research. Abstract
Salter AI, Ivey RG, Kennedy JJ, Voillet V, Rajan A, Alderman EJ, Voytovich UJ, Lin C, Sommermeyer D, Liu L et al..  2018.  Phosphoproteomic analysis of chimeric antigen receptor signaling reveals kinetic and quantitative differences that affect cell function.. Science signaling. 11(544) Abstract
Wang X, Naranjo A, Brown CE, Bautista C, Wong CLW, Chang W-C, Aguilar B, Ostberg JR, Riddell SR, Forman SJ et al..  2012.  Phenotypic and Functional Attributes of Lentivirus-modified CD19-specific Human CD8+ Central Memory T Cells Manufactured at Clinical Scale.. Journal of immunotherapy (Hagerstown, Md. : 1997). 35(9):689-701. Abstract
Wang X, Popplewell LL, Wagner JR, Naranjo A, Blanchard SM, Mott MR, Norris AP, Wong CLW, Urak RZ, Chang W-C et al..  2016.  Phase I studies of central-memory-derived CD19 CAR T cell therapy following autologous HSCT in patients with B-cell NHL.. Blood. 127(24):2980-2990. Abstract
Shibuya KC, Goel VK, Xiong W, Sham JG, Pollack SM, Leahy AM, Whiting SH, Yeh MM, Yee C, Riddell SR et al..  2014.  Pancreatic Ductal Adenocarcinoma Contains an Effector and Regulatory Immune Cell Infiltrate that Is Altered by Multimodal Neoadjuvant Treatment.. PloS one. 9(5):e96565. Abstract
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Robins HS, Srivastava SK, Campregher PV, Turtle CJ, Andriesen J, Riddell SR, Carlson CS, Warren EH.  2010.  Overlap and effective size of the human CD8+ T cell receptor repertoire.. Science translational medicine. 2(47):47ra64. Abstract