Center-Authored Papers

Filters: Author is Kiem, Hans-Peter  [Clear All Filters]
1994
Kiem HP, Darovsky B, von Kalle C, Goehle S, Stewart D, Graham T, Hackman R, Appelbaum FR, Deeg HJ, Miller AD.  1994.  Retrovirus-mediated gene transduction into canine peripheral blood repopulating cells.. Blood. 83(6):1467-73. Abstract
1996
Kiem HP, Darovsky B, von Kalle C, Goehle S, Graham T, Miller AD, Storb R, Schuening FG.  1996.  Long-term persistence of canine hematopoietic cells genetically marked by retrovirus vectors.. Human gene therapy. 7(1):89-96. Abstract
Miller AD, Bonham L, Alfano J, Kiem HP, Reynolds T, Wolgamot G.  1996.  A novel murine retrovirus identified during testing for helper virus in human gene transfer trials.. Journal of virology. 70(3):1804-9. Abstract
1997
Kiem HP, Heyward S, Winkler A, Potter J, Allen JM, Miller AD, Andrews RG.  1997.  Gene transfer into marrow repopulating cells: comparison between amphotropic and gibbon ape leukemia virus pseudotyped retroviral vectors in a competitive repopulation assay in baboons.. Blood. 90(11):4638-45. Abstract
Schuening F, Longo WL, Atkinson ME, Zaboikin M, Kiem HP, Sanders J, Scott CR, Storb R, Miller AD, Reynolds T et al..  1997.  Retrovirus-mediated transfer of the cDNA for human glucocerebrosidase into peripheral blood repopulating cells of patients with Gaucher's disease.. Human gene therapy. 8(17):2143-60.
1998
Kiem HP, Andrews RG, Morris J, Peterson L, Heyward S, Allen JM, Rasko JE, Potter J, Miller AD.  1998.  Improved gene transfer into baboon marrow repopulating cells using recombinant human fibronectin fragment CH-296 in combination with interleukin-6, stem cell factor, FLT-3 ligand, and megakaryocyte growth and development factor.. Blood. 92(6):1878-86. Abstract
1999
Kurre P, Kiem HP, Morris J, Heyward S, Battini JL, Miller AD.  1999.  Efficient transduction by an amphotropic retrovirus vector is dependent on high-level expression of the cell surface virus receptor.. Journal of virology. 73(1):495-500. Abstract
Kiem HP, McSweeney PA, Bruno B, Goerner M, Buron G, Morris J, Storb R, Miller AD.  1999.  Improved gene transfer into canine hematopoietic repopulating cells using CD34-enriched marrow cells in combination with a gibbon ape leukemia virus-pseudotype retroviral vector.. Gene therapy. 6(6):966-72. Abstract
2000
Andrews RG, Peterson LJ, Morris J, Potter J, Heyward S, Gough M, Bryant E, Kiem HP.  2000.  Differential engraftment of genetically modified CD34(+) and CD34(-) hematopoietic cell subsets in lethally irradiated baboons.. Experimental hematology. 28(5):508-18. Abstract
Shields LE, Kiem HP, Andrews RG.  2000.  Highly efficient gene transfer into preterm CD34 hematopoietic progenitor cells.. American journal of obstetrics and gynecology. 183(3):732-7. Abstract
2001
Kurre P, Morris J, Miller AD, Kiem HP.  2001.  Envelope fusion protein binding studies in an inducible model of retrovirus receptor expression and in CD34(+) cells emphasize limited transduction at low receptor levels.. Gene therapy. 8(8):593-9. Abstract
Kurre P, Morris J, Horn PA, Harkey MA, Andrews RG, Kiem HP.  2001.  Gene transfer into baboon repopulating cells: A comparison of Flt-3 Ligand and megakaryocyte growth and development factor versus IL-3 during ex vivo transduction.. Molecular therapy : the journal of the American Society of Gene Therapy. 3(6):920-7. Abstract
2002
Kurre P, Morris J, Andrews RG, Kohn DB, Kiem H-P.  2002.  Kinetics of fluorescence expression in nonhuman primates transplanted with GFP retrovirus-modified CD34 cells.. Molecular therapy : the journal of the American Society of Gene Therapy. 6(1):83-90. Abstract
Kiem H-P, Rasko JEJ, Morris J, Peterson L, Kurre P, Andrews RG.  2002.  Ex vivo selection for oncoretrovirally transduced green fluorescent protein-expressing CD34-enriched cells increases short-term engraftment of transduced cells in baboons.. Human gene therapy. 13(8):891-9. Abstract
Horn PA, Morris JC, Bukovsky AA, Andrews RG, Naldini L, Kurre P, Kiem H-P.  2002.  Lentivirus-mediated gene transfer into hematopoietic repopulating cells in baboons.. Gene therapy. 9(21):1464-71. Abstract
Schmidt M, Zickler P, Hoffmann G, Haas S, Wissler M, Muessig A, Tisdale JF, Kuramoto K, Andrews RG, Wu T et al..  2002.  Polyclonal long-term repopulating stem cell clones in a primate model.. Blood. 100(8):2737-43. Abstract
2003
Horn PA, Thomasson BM, Wood BL, Andrews RG, Morris JC, Kiem H-P.  2003.  Distinct hematopoietic stem/progenitor cell populations are responsible for repopulating NOD/SCID mice compared with nonhuman primates.. Blood. 102(13):4329-35. Abstract
Storek J, Gillespy T, Lu H, Joseph A, Dawson MA, Gough M, Morris J, Hackman RC, Horn PA, Sale GE et al..  2003.  Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys.. Blood. 101(10):4209-18. Abstract
2004
Kiem H-P, Sellers S, Thomasson B, Morris JC, Tisdale JF, Horn PA, Hematti P, Adler R, Kuramoto K, Calmels B et al..  2004.  Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia.. Molecular therapy : the journal of the American Society of Gene Therapy. 9(3):389-95. Abstract
2005
Lu H, Zhao Z, Kalina T, Gillespy T, Liggitt D, Andrews RG, Maloney DG, Kiem H-P, Storek J.  2005.  Interleukin-7 improves reconstitution of antiviral CD4 T cells.. Clinical immunology (Orlando, Fla.). 114(1):30-41. Abstract
Kalina T, Lu H, Zhao Z, Blewett E, Dittmer DP, Randolph-Habecker J, Maloney DG, Andrews RG, Kiem H-P, Storek J.  2005.  De novo generation of CD4 T cells against viruses present in the host during immune reconstitution.. Blood. 105(6):2410-4. Abstract
2008
Zhang X-B, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries KR, Kiem H-P.  2008.  High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.. The Journal of clinical investigation. 118(4):1502-10. Abstract
Seal S, Hockenbery DM, Spaulding EY, Kiem H-P, Abbassi N, Deeg HJ.  2008.  Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals.. Experimental hematology. 36(12):1660-72. Abstract
Flowers MED, Storer BE, Carpenter PA, Rezvani AR, Vigorito AC, Campregher PV, Moravec C, Kiem H-P, Fero ML, Georges GE et al..  2008.  Treatment change as a predictor of outcome among patients with classic chronic graft-versus-host disease.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 14(12):1380-4. Abstract
Piasecki JC, Beagles K, Beard BC, Riddell SR, Kiem H-P.  2008.  Induction of transgene-specific cytotoxic T lymphocyte responses after transplantation of gene-modified CD34+ cells despite nonablative immunosuppressive conditioning.. Human gene therapy. 19(1):103-7. Abstract