Center-Authored Papers

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Xenograft Model Antitumor Assays
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Tumor Cells, Cultured
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Transfection
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Temperature
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Substrate Specificity
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Rats
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Protein Engineering
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Protein Denaturation
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Prodrugs
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Neoplasms
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Mutation
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Mutant Proteins
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Models, Molecular
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Mice, Nude
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Mice, Inbred BALB C
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
MICE
Stolworthy TS, Korkegian AM, Willmon CL, Ardiani A, Cundiff J, Stoddard BL, Black ME.  2008.  Yeast cytosine deaminase mutants with increased thermostability impart sensitivity to 5-fluorocytosine.. Journal of molecular biology. 377(3):854-69. Abstract
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Humans
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
HCT116 Cells
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract
Gene Therapy
Fuchita M, Ardiani A, Zhao L, Serve K, Stoddard BL, Black ME.  2009.  Bacterial cytosine deaminase mutants created by molecular engineering show improved 5-fluorocytosine-mediated cell killing in vitro and in vivo.. Cancer research. 69(11):4791-9. Abstract