Center-Authored Papers

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2009
Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM.  2009.  High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.. Nucleic acids research. 37(20):6871-80. Abstract
Thyme SB, Jarjour J, Takeuchi R, Havranek JJ, Ashworth J, Scharenberg AM, Stoddard BL, Baker D.  2009.  Exploitation of binding energy for catalysis and design.. Nature. 461(7268):1300-4. Abstract
2012
Taylor GK, Petrucci LH, Lambert AR, Baxter SK, Jarjour J, Stoddard BL.  2012.  LAHEDES: the LAGLIDADG homing endonuclease database and engineering server.. Nucleic acids research. 40(W1):W110-W116. Abstract
Baxter S, Lambert AR, Kuhar R, Jarjour J, Kulshina N, Parmeggiani F, Danaher P, Gano J, Baker D, Stoddard BL et al..  2012.  Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases.. Nucleic acids research. Abstract
Jacoby K, Metzger M, Shen BW, Certo MT, Jarjour J, Stoddard BL, Scharenberg AM.  2012.  Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space.. Nucleic acids research. 40(11):4954-4964. Abstract
2013
Boissel S, Jarjour J, Astrakhan A, Adey A, Gouble A, Duchateau P, Shendure J, Stoddard BL, Certo MT, Baker D et al..  2014.  megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.. Nucleic acids research. 42(4):2591-601. Abstract
Chan Y-S, Takeuchi R, Jarjour J, Huen DS, Stoddard BL, Russell S.  2013.  The Design and In Vivo Evaluation of Engineered I-OnuI-Based Enzymes for HEG Gene Drive.. PloS one. 8(9):e74254. Abstract
Basic Sciences Division
Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM.  2009.  High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.. Nucleic acids research. 37(20):6871-80. Abstract
Jacoby K, Metzger M, Shen BW, Certo MT, Jarjour J, Stoddard BL, Scharenberg AM.  2012.  Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space.. Nucleic acids research. 40(11):4954-4964. Abstract
Chan Y-S, Takeuchi R, Jarjour J, Huen DS, Stoddard BL, Russell S.  2013.  The Design and In Vivo Evaluation of Engineered I-OnuI-Based Enzymes for HEG Gene Drive.. PloS one. 8(9):e74254. Abstract
Boissel S, Jarjour J, Astrakhan A, Adey A, Gouble A, Duchateau P, Shendure J, Stoddard BL, Certo MT, Baker D et al..  2014.  megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.. Nucleic acids research. 42(4):2591-601. Abstract
Baxter S, Lambert AR, Kuhar R, Jarjour J, Kulshina N, Parmeggiani F, Danaher P, Gano J, Baker D, Stoddard BL et al..  2012.  Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases.. Nucleic acids research. Abstract
Taylor GK, Petrucci LH, Lambert AR, Baxter SK, Jarjour J, Stoddard BL.  2012.  LAHEDES: the LAGLIDADG homing endonuclease database and engineering server.. Nucleic acids research. 40(W1):W110-W116. Abstract
Thyme SB, Jarjour J, Takeuchi R, Havranek JJ, Ashworth J, Scharenberg AM, Stoddard BL, Baker D.  2009.  Exploitation of binding energy for catalysis and design.. Nature. 461(7268):1300-4. Abstract
Binding Sites
Thyme SB, Jarjour J, Takeuchi R, Havranek JJ, Ashworth J, Scharenberg AM, Stoddard BL, Baker D.  2009.  Exploitation of binding energy for catalysis and design.. Nature. 461(7268):1300-4. Abstract
Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM.  2009.  High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.. Nucleic acids research. 37(20):6871-80. Abstract
Biocatalysis
Thyme SB, Jarjour J, Takeuchi R, Havranek JJ, Ashworth J, Scharenberg AM, Stoddard BL, Baker D.  2009.  Exploitation of binding energy for catalysis and design.. Nature. 461(7268):1300-4. Abstract
CATALYSIS
Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM.  2009.  High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.. Nucleic acids research. 37(20):6871-80. Abstract
Center-Authored Paper
Taylor GK, Petrucci LH, Lambert AR, Baxter SK, Jarjour J, Stoddard BL.  2012.  LAHEDES: the LAGLIDADG homing endonuclease database and engineering server.. Nucleic acids research. 40(W1):W110-W116. Abstract
Jacoby K, Metzger M, Shen BW, Certo MT, Jarjour J, Stoddard BL, Scharenberg AM.  2012.  Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space.. Nucleic acids research. 40(11):4954-4964. Abstract
Boissel S, Jarjour J, Astrakhan A, Adey A, Gouble A, Duchateau P, Shendure J, Stoddard BL, Certo MT, Baker D et al..  2014.  megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.. Nucleic acids research. 42(4):2591-601. Abstract
Computational Biology
Thyme SB, Jarjour J, Takeuchi R, Havranek JJ, Ashworth J, Scharenberg AM, Stoddard BL, Baker D.  2009.  Exploitation of binding energy for catalysis and design.. Nature. 461(7268):1300-4. Abstract
Computer Simulation
Thyme SB, Jarjour J, Takeuchi R, Havranek JJ, Ashworth J, Scharenberg AM, Stoddard BL, Baker D.  2009.  Exploitation of binding energy for catalysis and design.. Nature. 461(7268):1300-4. Abstract
December 2013
Boissel S, Jarjour J, Astrakhan A, Adey A, Gouble A, Duchateau P, Shendure J, Stoddard BL, Certo MT, Baker D et al..  2014.  megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering.. Nucleic acids research. 42(4):2591-601. Abstract
Deoxyribonucleases, Type II Site-Specific
Jarjour J, West-Foyle H, Certo MT, Hubert CG, Doyle L, Getz MM, Stoddard BL, Scharenberg AM.  2009.  High-resolution profiling of homing endonuclease binding and catalytic specificity using yeast surface display.. Nucleic acids research. 37(20):6871-80. Abstract