Center-Authored Papers

Filters: Author is Lambert, Abigail R  [Clear All Filters]
Journal Article
Siegel JB, Zanghellini A, Lovick HM, Kiss G, Lambert AR, St Clair JL, Gallaher JL, Hilvert D, Gelb MH, Stoddard BL et al..  2010.  Computational design of an enzyme catalyst for a stereoselective bimolecular Diels-Alder reaction.. Science (New York, N.Y.). 329(5989):309-13. Abstract
Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K et al..  2012.  Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.. Nature methods. 9(10):973-5. Abstract
Werther R, Hallinan JP, Lambert AR, Havens K, Pogson M, Jarjour J, Galizi R, Windbichler N, Crisanti A, Nolan T et al..  2017.  Crystallographic analyses illustrate significant plasticity and efficient recoding of meganuclease target specificity.. Nucleic acids research. Abstract
Baxter S, Lambert AR, Kuhar R, Jarjour J, Kulshina N, Parmeggiani F, Danaher P, Gano J, Baker D, Stoddard BL et al..  2012.  Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases.. Nucleic acids research. Abstract
Mak AN-S, Lambert AR, Stoddard BL.  2010.  Folding, DNA recognition, and function of GIY-YIG endonucleases: crystal structures of R.Eco29kI.. Structure (London, England : 1993). 18(10):1321-31. Abstract
Lambert AR, Hallinan JP, Shen BW, Chik JK, Bolduc JM, Kulshina N, Robins LI, Kaiser BK, Jarjour J, Havens K et al..  2016.  Indirect DNA Sequence Recognition and Its Impact on Nuclease Cleavage Activity.. Structure (London, England : 1993). Abstract
Taylor GK, Petrucci LH, Lambert AR, Baxter SK, Jarjour J, Stoddard BL.  2012.  LAHEDES: the LAGLIDADG homing endonuclease database and engineering server.. Nucleic acids research. 40(W1):W110-W116. Abstract
Lambert AR, Sussman D, Shen B, Maunus R, Nix J, Samuelson J, Xu S-Y, Stoddard BL.  2008.  Structures of the rare-cutting restriction endonuclease NotI reveal a unique metal binding fold involved in DNA binding.. Structure (London, England : 1993). 16(4):558-69. Abstract
Takeuchi R, Lambert AR, Mak AN-S, Jacoby K, Dickson RJ, Gloor GB, Scharenberg AM, Edgell DR, Stoddard BL.  2011.  Tapping natural reservoirs of homing endonucleases for targeted gene modification.. Proceedings of the National Academy of Sciences of the United States of America. 108(32):13077-82. Abstract
Niyonzima N, Lambert AR, Werther R, De Silva Feelixge H, Roychoudhury P, Greninger AL, Stone D, Stoddard BL, Jerome KR.  2017.  Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses.. Protein engineering, design & selection : PEDS. 30(7):503-522. Abstract