Center-Authored Papers

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Virus Replication
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H et al..  2015.  Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.. Nature. 517(7534):381-5. Abstract
Virus Latency
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H et al..  2015.  Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.. Nature. 517(7534):381-5. Abstract
Viral Load
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H et al..  2015.  Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.. Nature. 517(7534):381-5. Abstract
Vaccines
Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG et al..  2012.  NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells.. Nature. 484(7395):510-3. Abstract
Transplantation, Heterologous
Rongvaux A, Willinger T, Martinek J, Strowig T, Gearty SV, Teichmann LL, Saito Y, Marches F, Halene S, Palucka KA et al..  2014.  Development and function of human innate immune cells in a humanized mouse model.. Nature biotechnology. 32(4):364-72. Abstract
Rongvaux A, Takizawa H, Strowig T, Willinger T, Eynon EE, Flavell RA, Manz MG.  2013.  Human hemato-lymphoid system mice: current use and future potential for medicine.. Annual review of immunology. 31:635-74. Abstract
Translational Medical Research
Willinger T, Rongvaux A, Strowig T, Manz MG, Flavell RA.  2011.  Improving human hemato-lymphoid-system mice by cytokine knock-in gene replacement.. Trends in immunology. 32(7):321-7. Abstract
Rongvaux A, Takizawa H, Strowig T, Willinger T, Eynon EE, Flavell RA, Manz MG.  2013.  Human hemato-lymphoid system mice: current use and future potential for medicine.. Annual review of immunology. 31:635-74. Abstract
Transgenes
Strowig T, Rongvaux A, Rathinam C, Takizawa H, Borsotti C, Philbrick W, Eynon EE, Manz MG, Flavell RA.  2011.  Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.. Proceedings of the National Academy of Sciences of the United States of America. 108(32):13218-23. Abstract
T-Lymphocytes, Helper-Inducer
Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG et al..  2012.  NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells.. Nature. 484(7395):510-3. Abstract
T-Lymphocytes, Cytotoxic
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H et al..  2015.  Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.. Nature. 517(7534):381-5. Abstract
T-Lymphocytes
Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG et al..  2012.  NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells.. Nature. 484(7395):510-3. Abstract
RNA, Viral
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H et al..  2015.  Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.. Nature. 517(7534):381-5. Abstract
Receptors, Immunologic
Strowig T, Rongvaux A, Rathinam C, Takizawa H, Borsotti C, Philbrick W, Eynon EE, Manz MG, Flavell RA.  2011.  Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.. Proceedings of the National Academy of Sciences of the United States of America. 108(32):13218-23. Abstract
Neoplasms, Experimental
Rongvaux A, Willinger T, Martinek J, Strowig T, Gearty SV, Teichmann LL, Saito Y, Marches F, Halene S, Palucka KA et al..  2014.  Development and function of human innate immune cells in a humanized mouse model.. Nature biotechnology. 32(4):364-72. Abstract
Myeloid Cells
Rongvaux A, Willinger T, Martinek J, Strowig T, Gearty SV, Teichmann LL, Saito Y, Marches F, Halene S, Palucka KA et al..  2014.  Development and function of human innate immune cells in a humanized mouse model.. Nature biotechnology. 32(4):364-72. Abstract
Mutation
Deng K, Pertea M, Rongvaux A, Wang L, Durand CM, Ghiaur G, Lai J, McHugh HL, Hao H, Zhang H et al..  2015.  Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations.. Nature. 517(7534):381-5. Abstract
Models, Animal
Rongvaux A, Takizawa H, Strowig T, Willinger T, Eynon EE, Flavell RA, Manz MG.  2013.  Human hemato-lymphoid system mice: current use and future potential for medicine.. Annual review of immunology. 31:635-74. Abstract
Mice, Transgenic
Strowig T, Rongvaux A, Rathinam C, Takizawa H, Borsotti C, Philbrick W, Eynon EE, Manz MG, Flavell RA.  2011.  Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.. Proceedings of the National Academy of Sciences of the United States of America. 108(32):13218-23. Abstract
Rongvaux A, Willinger T, Martinek J, Strowig T, Gearty SV, Teichmann LL, Saito Y, Marches F, Halene S, Palucka KA et al..  2014.  Development and function of human innate immune cells in a humanized mouse model.. Nature biotechnology. 32(4):364-72. Abstract
Mice, Knockout
Strowig T, Rongvaux A, Rathinam C, Takizawa H, Borsotti C, Philbrick W, Eynon EE, Manz MG, Flavell RA.  2011.  Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.. Proceedings of the National Academy of Sciences of the United States of America. 108(32):13218-23. Abstract
Mice, Inbred BALB C
Strowig T, Rongvaux A, Rathinam C, Takizawa H, Borsotti C, Philbrick W, Eynon EE, Manz MG, Flavell RA.  2011.  Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.. Proceedings of the National Academy of Sciences of the United States of America. 108(32):13218-23. Abstract
Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG et al..  2012.  NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells.. Nature. 484(7395):510-3. Abstract
MICE
Rongvaux A, Willinger T, Martinek J, Strowig T, Gearty SV, Teichmann LL, Saito Y, Marches F, Halene S, Palucka KA et al..  2014.  Development and function of human innate immune cells in a humanized mouse model.. Nature biotechnology. 32(4):364-72. Abstract
Willinger T, Rongvaux A, Strowig T, Manz MG, Flavell RA.  2011.  Improving human hemato-lymphoid-system mice by cytokine knock-in gene replacement.. Trends in immunology. 32(7):321-7. Abstract