Center-Authored Papers

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Adair JE, Chandrasekaran D, Sghia-Hughes G, Haworth KG, Woolfrey AE, Burroughs LM, Choi GY, Becker PS, Kiem H-P.  2018.  Novel lineage depletion preserves autologous blood stem cells for gene therapy of Fanconi anemia complementation group A.. Haematologica. Abstract
Adair JE, Waters T, Haworth KG, Kubek SP, Trobridge GD, Hocum JD, Heimfeld S, Kiem H-P.  2016.  Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy.. Nature communications. 7:13173. Abstract
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Haworth KG, Peterson CW, Kiem H-P.  2017.  CCR5-edited gene therapies for HIV cure: Closing the door to viral entry.. Cytotherapy. Abstract
Haworth KG, Ironside C, Norgaard ZK, Obenza WM, Adair JE, Kiem H-P.  2017.  In Vivo Murine-Matured Human CD3(+) Cells as a Preclinical Model for T Cell-Based Immunotherapies.. Molecular therapy. Methods & clinical development. 6:17-30. Abstract
Haworth KG, Ironside C, Ramirez MA, Weitz S, Beard BC, Schwartz J, Adair JE, Kiem H-P.  2018.  Minimal conditioning in Fanconi anemia promotes multi-lineage marrow engraftment at ten-fold lower cell doses.. The journal of gene medicine. :e3050. Abstract
Haworth KG, Schefter LE, Norgaard ZK, Ironside C, Adair JE, Kiem H-P.  2018.  HIV infection results in clonal expansions containing integrations within pathogenesis-related biological pathways.. JCI insight. 3(13) Abstract
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Peterson CW, Haworth KG, Polacino P, Huang M-L, Sykes C, Obenza WM, Repetto AC, Kashuba A, Bumgarner R, De Rosa SC et al..  2015.  Lack of viral control and development of combination antiretroviral therapy escape mutations in macaques after bone marrow transplantation.. AIDS (London, England). 29(13):1597-606. Abstract
Peterson CW, Haworth KG, Burke BP, Polacino P, Norman KK, Adair JE, Hu S-lok, Bartlett JS, Symonds GP, Kiem H-P.  2016.  Multilineage polyclonal engraftment of Cal-1 gene-modified cells and in vivo selection after SHIV infection in a nonhuman primate model of AIDS.. Molecular therapy. Methods & clinical development. 3:16007. Abstract
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Radtke S, Adair JE, Giese MA, Chan Y-Y, Norgaard ZK, Enstrom M, Haworth KG, Schefter LE, Kiem H-P.  2017.  A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates.. Science translational medicine. 9(414) Abstract
Radtke S, Haworth KG, Kiem H-P.  2016.  The frequency of multipotent CD133(+)CD45RA(-)CD34(+) hematopoietic stem cells is not increased in fetal liver compared to adult stem cell sources.. Experimental hematology. 44(6):502-507. Abstract
Richter M, Saydaminova K, Yumul R, Krishnan R, Liu J, Nagy E-E, Singh M, Izsvák Z, Cattaneo R, Uckert W et al..  2016.  In vivo transduction of primitive hematopoietic stem cells after mobilization and intravenous injection of integrating adenovirus vectors.. Blood. Abstract