Center-Authored Papers

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Zeng C, Guo X, Long J, Kuchenbaecker KB, Droit A, Michailidou K, Ghoussaini M, Kar S, Freeman A, Hopper JL et al..  2016.  Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.. Breast cancer research : BCR. 18(1):64. Abstract
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Song H, Ramus SJ, Tyrer J, Bolton KL, Gentry-Maharaj A, Wozniak E, Anton-Culver H, Chang-Claude J, Cramer DW, DiCioccio R et al..  2009.  A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.. Nature genetics. 41(9):996-1000. Abstract
Shen H, Fridley BL, Song H, Lawrenson K, Cunningham JM, Ramus SJ, Cicek MS, Tyrer J, Stram D, Larson MC et al..  2013.  Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer.. Nature communications. 4:1628. Abstract
Schmidt MK, Hogervorst F, van Hien R, Cornelissen S, Broeks A, Adank MA, Meijers H, Waisfisz Q, Hollestelle A, Schutte M et al..  2016.  Age- and Tumor Subtype-Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 34(23):2750-60. Abstract
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Phelan CM, Kuchenbaecker KB, Tyrer JP, Kar SP, Lawrenson K, Winham SJ, Dennis J, Pirie A, Riggan MJ, Chornokur G et al..  2017.  Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.. Nature genetics. Abstract
Pharoah PDP, Tsai Y-Y, Ramus SJ, Phelan CM, Goode EL, Lawrenson K, Buckley M, Fridley BL, Tyrer JP, Shen H et al..  2013.  GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.. Nature genetics. 45(4):362-70,370e1-2. Abstract
Permuth-Wey J, Lawrenson K, Shen HC, Velkova A, Tyrer JP, Chen Z, Lin H-Y, Chen AY, Tsai Y-Y, Qu X et al..  2013.  Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.. Nature communications. 4:1627. Abstract
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Ong J-S, Cuellar-Partida G, Lu Y, Australian Ovarian Cancer Study, Fasching PA, Hein A, Burghaus S, Beckmann MW, Lambrechts D, Van Nieuwenhuysen E et al..  2016.  Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study.. International journal of epidemiology. Abstract
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Minlikeeva AN, Freudenheim JL, Cannioto RA, Szender BJ, Eng KH, Modugno F, Ness RB, Lamonte MJ, Friel G, Segal BH et al..  2017.  History of hypertension, heart disease, and diabetes and ovarian cancer patient survival: evidence from the ovarian cancer association consortium.. Cancer causes & control : CCC. Abstract
Minlikeeva AN, Freudenheim JL, Cannioto RA, Eng KH, Szender BJ, Mayor P, Etter JL, Cramer DW, Diergaarde B, Doherty JA et al..  2017.  History of thyroid disease and survival of ovarian cancer patients: results from the Ovarian Cancer Association Consortium, a brief report.. British journal of cancer. Abstract
Mavaddat N, Pharoah PDP, Michailidou K, Tyrer J, Brook MN, Bolla MK, Wang Q, Dennis J, Dunning AM, Shah M et al..  2015.  Prediction of breast cancer risk based on profiling with common genetic variants.. Journal of the National Cancer Institute. 107(5) Abstract
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Lu Y, Cuellar G, Painter JN, Nyholt D, Morris AP, Fasching PA, Hein A, Burghaus S, Beckmann MW, Lambrechts D et al..  2015.  Shared genetics underlying epidemiological association between endometriosis and ovarian cancer.. Human molecular genetics. 24(20):5955-5964. Abstract
Lee AW, Tyrer JP, Doherty JA, Stram DA, Kupryjanczyk J, Dansonka-Mieszkowska A, Plisiecka-Halasa J, Spiewankiewicz B, Myers EJ, Chenevix-Trench G et al..  2015.  Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study.. Gynecologic oncology. 136(3):542-8. Abstract
Lawrenson K, Li Q, Kar S, Seo J-H, Tyrer J, Spindler TJ, Lee J, Chen Y, Karst A, Drapkin R et al..  2015.  Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer.. Nature communications. 6:8234. Abstract
Lawrenson K, Iversen ES, Tyrer J, Weber RP, Concannon P, Hazelett DJ, Li Q, Marks JR, Berchuck A, Lee JM et al..  2015.  Common Variants at the CHEK2 Gene Locus and Risk of Epithelial Ovarian Cancer.. Carcinogenesis. 36(11):1341-1353. Abstract
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Kuchenbaecker KB, Ramus SJ, Tyrer J, Lee A, Shen HC, Beesley J, Lawrenson K, McGuffog L, Healey S, Lee JM et al..  2015.  Identification of six new susceptibility loci for invasive epithelial ovarian cancer.. Nature genetics. 47(2):164-71. Abstract
Kelemen LE, Terry KL, Goodman MT, Webb PM, Bandera EV, McGuire V, Rossing MA, Wang Q, Dicks E, Tyrer JP et al..  2014.  Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk.. Molecular nutrition & food research. Abstract
Kar SP, Tyrer JP, Li Q, Lawrenson K, Aben KKH, Anton-Culver H, Antonenkova N, Chenevix-Trench G, Baker H, Bandera E et al..  2015.  Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 24(10):1574-1584. Abstract
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Johnatty S, Tyrer JP, Kar SP, Beesley J, Lu Y, Gao B, Fasching PA, Hein A, Ekici AB, Beckmann MW et al..  2015.  Genome-wide analysis identifies novel loci associated with ovarian cancer outcomes: findings from the Ovarian Cancer Association Consortium.. Clinical cancer research : an official journal of the American Association for Cancer Research. 21(23):5264-5276. Abstract
Jim HSL, Lin H-Y, Tyrer JP, Lawrenson K, Dennis J, Chornokur G, Chen Z, Chen AY, Permuth-Wey J, Aben KKH et al..  2015.  Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).. Journal of genetics and genome research. 2(2) Abstract
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Hein R, Maranian M, Hopper JL, Kapuscinski MK, Southey MC, Park DJ, Schmidt MK, Broeks A, Hogervorst FBL, Bueno-de-Mesquit BH et al..  2012.  Comparison of 6q25 Breast Cancer Hits from Asian and European Genome Wide Association Studies in the Breast Cancer Association Consortium (BCAC).. PloS one. 7(8):e42380. Abstract
Hampras SS, Sucheston-Campbell LE, Cannioto R, Chang-Claude J, Modugno F, Dörk T, Hillemanns P, Preus L, Knutson KL, Wallace PK et al..  2016.  Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer.. Oncotarget. Abstract
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Goode EL, Chenevix-Trench G, Song H, Ramus SJ, Notaridou M, Lawrenson K, Widschwendter M, Vierkant RA, Larson MC, Kjaer SK et al..  2010.  A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.. Nature genetics. 42(10):874-9. Abstract
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Figueroa JD, Garcia-Closas M, Humphreys M, Platte R, Hopper JL, Southey MC, Apicella C, Hammet F, Schmidt MK, Broeks A et al..  2011.  Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: Findings from the Breast Cancer Association Consortium.. Human molecular genetics. 20(23):4693-4706. Abstract
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Earp MA, Kelemen LE, Magliocco AM, Swenerton KD, Chenevix-Trench G, Lu Y, Hein A, Ekici AB, Beckmann MW, Fasching PA et al..  2013.  Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.. Human genetics. Abstract