Center-Authored Papers

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Journal Article
Hampras SS, Sucheston-Campbell LE, Cannioto R, Chang-Claude J, Modugno F, Dörk T, Hillemanns P, Preus L, Knutson KL, Wallace PK et al..  2016.  Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer.. Oncotarget. Abstract
Lawrenson K, Li Q, Kar S, Seo J-H, Tyrer J, Spindler TJ, Lee J, Chen Y, Karst A, Drapkin R et al..  2015.  Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer.. Nature communications. 6:8234. Abstract
Chornokur G, Lin H-Y, Tyrer JP, Lawrenson K, Dennis J, Amankwah EK, Qu X, Tsai Y-Y, Jim HSL, Chen Z et al..  2015.  Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk.. PloS one. 10(6):e0128106. Abstract
Lawrenson K, Iversen ES, Tyrer J, Weber RP, Concannon P, Hazelett DJ, Li Q, Marks JR, Berchuck A, Lee JM et al..  2015.  Common Variants at the CHEK2 Gene Locus and Risk of Epithelial Ovarian Cancer.. Carcinogenesis. 36(11):1341-1353. Abstract
Kelemen LE, Terry KL, Goodman MT, Webb PM, Bandera EV, McGuire V, Rossing MA, Wang Q, Dicks E, Tyrer JP et al..  2014.  Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk.. Molecular nutrition & food research. Abstract
Amankwah EK, Lin H-Y, Tyrer JP, Lawrenson K, Dennis J, Chornokur G, Aben KKH, Anton-Culver H, Antonenkova N, Bruinsma F et al..  2015.  Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk.. Genetic epidemiology. Abstract
Udler MS, Ahmed S, Healey CS, Meyer K, Struewing J, Maranian M, Kwon EM, Zhang J, Tyrer J, Karlins E et al..  2010.  Fine scale mapping of the breast cancer 16q12 locus.. Human molecular genetics. 19(12):2507-15. Abstract
Kote-Jarai Z, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Dadaev T, Jugurnauth-Little S, Ross-Adams H, Al Olama AA, Benlloch S, Halim S et al..  2013.  Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.. Human molecular genetics. Abstract
Song H, Ramus SJ, Tyrer J, Bolton KL, Gentry-Maharaj A, Wozniak E, Anton-Culver H, Chang-Claude J, Cramer DW, DiCioccio R et al..  2009.  A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.. Nature genetics. 41(9):996-1000. Abstract
Earp MA, Kelemen LE, Magliocco AM, Swenerton KD, Chenevix-Trench G, Lu Y, Hein A, Ekici AB, Beckmann MW, Fasching PA et al..  2013.  Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.. Human genetics. Abstract
Pharoah PDP, Tsai Y-Y, Ramus SJ, Phelan CM, Goode EL, Lawrenson K, Buckley M, Fridley BL, Tyrer JP, Shen H et al..  2013.  GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer.. Nature genetics. 45(4):362-70,370e1-2. Abstract
Phelan CM, Kuchenbaecker KB, Tyrer JP, Kar SP, Lawrenson K, Winham SJ, Dennis J, Pirie A, Riggan MJ, Chornokur G et al..  2017.  Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.. Nature genetics. Abstract
Eeles RA, Al Olama AA, Benlloch S, Saunders EJ, Leongamornlert DA, Tymrakiewicz M, Ghoussaini M, Luccarini C, Dennis J, Jugurnauth-Little S et al..  2013.  Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.. Nature genetics. 45(4):385-91,391e1-2. Abstract
Kuchenbaecker KB, Ramus SJ, Tyrer J, Lee A, Shen HC, Beesley J, Lawrenson K, McGuffog L, Healey S, Lee JM et al..  2015.  Identification of six new susceptibility loci for invasive epithelial ovarian cancer.. Nature genetics. 47(2):164-71. Abstract
Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE et al..  2013.  Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.. Nature genetics. 45(4):371-84,384e1-2. Abstract
Kar SP, Tyrer JP, Li Q, Lawrenson K, Aben KKH, Anton-Culver H, Antonenkova N, Chenevix-Trench G, Baker H, Bandera E et al..  2015.  Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 24(10):1574-1584. Abstract
Southey MC, Goldgar DE, Winqvist R, Pylkäs K, Couch F, Tischkowitz M, Foulkes WD, Dennis J, Michailidou K, van Rensburg EJ et al..  2016.  PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.. Journal of medical genetics. Abstract