Center-Authored Papers

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Lawrenson K, Li Q, Kar S, Seo J-H, Tyrer J, Spindler TJ, Lee J, Chen Y, Karst A, Drapkin R et al..  2015.  Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer.. Nature communications. 6:8234. Abstract
Lawrenson K, Iversen ES, Tyrer J, Weber RP, Concannon P, Hazelett DJ, Li Q, Marks JR, Berchuck A, Lee JM et al..  2015.  Common Variants at the CHEK2 Gene Locus and Risk of Epithelial Ovarian Cancer.. Carcinogenesis. 36(11):1341-1353. Abstract
Fehringer G, Kraft P, Pharoah PDP, Eeles RA, Chatterjee N, Schumacher FR, Schildkraut JM, Lindstrom S, Brennan P, Bickeböller H et al..  2016.  Cross-cancer genome-wide analysis of lung, ovary, breast, prostate and colorectal cancer reveals novel pleiotropic associations.. Cancer research. 76(17):5103-5114. Abstract
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Kar SP, Adler E, Tyrer J, Hazelett D, Anton-Culver H, Bandera EV, Beckmann MW, Berchuck A, Bogdanova N, Brinton L et al..  2017.  Enrichment of putative PAX8 target genes at serous epithelial ovarian cancer susceptibility loci.. British journal of cancer. Abstract
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Lawrenson K, Kar S, McCue K, Kuchenbaeker K, Michailidou K, Tyrer J, Beesley J, Ramus SJ, Li Q, Delgado MK et al..  2016.  Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.. Nature communications. 7:12675. Abstract
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Kar SP, Beesley J, Al Olama AA, Michailidou K, Tyrer J, Kote-Jarai Z, Lawrenson K, Lindstrom S, Ramus SJ, Thompson DJ et al..  2016.  Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types.. Cancer discovery. 6(9):1052-1067. Abstract
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Kuchenbaecker KB, Ramus SJ, Tyrer J, Lee A, Shen HC, Beesley J, Lawrenson K, McGuffog L, Healey S, Lee JM et al..  2015.  Identification of six new susceptibility loci for invasive epithelial ovarian cancer.. Nature genetics. 47(2):164-71. Abstract
Han Y, Hazelett DJ, Wiklund F, Schumacher FR, Stram DO, Berndt SI, Wang Z, Rand KA, Hoover RN, Machiela MJ et al..  2015.  Integration of multiethnic fine-mapping and genomic annotation to prioritize candidate functional SNPs at prostate cancer susceptibility regions.. Human molecular genetics. 24(19):5603-5618. Abstract
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Al Olama AA, Kote-Jarai Z, Berndt SI, Conti DV, Schumacher F, Han Y, Benlloch S, Hazelett DJ, Wang Z, Saunders E et al..  2014.  A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancer.. Nature genetics. 46(10):1103-9. Abstract
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Kar SP, Tyrer JP, Li Q, Lawrenson K, Aben KKH, Anton-Culver H, Antonenkova N, Chenevix-Trench G, Baker H, Bandera E et al..  2015.  Network-based integration of GWAS and gene expression identifies a HOX-centric network associated with serous ovarian cancer risk.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 24(10):1574-1584. Abstract