Center-Authored Papers

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Zeng C, Guo X, Long J, Kuchenbaecker KB, Droit A, Michailidou K, Ghoussaini M, Kar S, Freeman A, Hopper JL et al..  2016.  Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.. Breast cancer research : BCR. 18(1):64. Abstract
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Wyman SK, Parkin RK, Mitchell PS, Fritz BR, O'Briant K, Godwin AK, Urban ND, Drescher CW, Knudsen BS, Tewari M.  2009.  Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries.. PloS one. 4(4):e5311. Abstract
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Schilder RJ, Pathak HB, Lokshin AE, Holloway RW, Alvarez RD, Aghajanian C, Min H, Devarajan K, Ross E, Drescher CW et al..  2009.  Phase II trial of single agent cetuximab in patients with persistent or recurrent epithelial ovarian or primary peritoneal carcinoma with the potential for dose escalation to rash.. Gynecologic oncology. 113(1):21-7. Abstract
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Phelan CM, Kuchenbaecker KB, Tyrer JP, Kar SP, Lawrenson K, Winham SJ, Dennis J, Pirie A, Riggan MJ, Chornokur G et al..  2017.  Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.. Nature genetics. Abstract
Pharoah PDP, Palmieri RT, Ramus SJ, Gayther SA, Andrulis IL, Anton-Culver H, Antonenkova N, Antoniou AC, Goldgar D, Beattie MS et al..  2011.  The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing.. Clinical cancer research : an official journal of the American Association for Cancer Research. 17(11):3742-50. Abstract
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Marks JR, Anderson KS, Engstrom P, Godwin AK, Esserman LJ, Longton G, Iversen ES, Mathew A, Patriotis C, Pepe MS.  2015.  Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 24(2):435-41. Abstract
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Lawrenson K, Kar S, McCue K, Kuchenbaeker K, Michailidou K, Tyrer J, Beesley J, Ramus SJ, Li Q, Delgado MK et al..  2016.  Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.. Nature communications. 7:12675. Abstract
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Kuchenbaecker KB, Ramus SJ, Tyrer J, Lee A, Shen HC, Beesley J, Lawrenson K, McGuffog L, Healey S, Lee JM et al..  2015.  Identification of six new susceptibility loci for invasive epithelial ovarian cancer.. Nature genetics. 47(2):164-71. Abstract
Knouf EC, Garg K, Arroyo JD, Correa Y, Sarkar D, Parkin RK, Wurz K, O'Briant KC, Godwin AK, Urban ND et al..  2012.  An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription.. Nucleic acids research. 40(2):499-510. Abstract
Kanetsky PA, Mitra N, Vardhanabhuti S, Vaughn DJ, Li M, Ciosek SL, Letrero R, D'Andrea K, Vaddi M, Doody DR et al..  2011.  A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility.. Human molecular genetics. 20(15):3109-17. Abstract
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Hollestelle A, van der Baan FH, Berchuck A, Johnatty SE, Aben KK, Agnarsson BA, Aittomäki K, Alducci E, Andrulis IL, Anton-Culver H et al..  2016.  No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer. Gynecologic Oncology. 141(2):386-401. Abstract
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Goode EL, Chenevix-Trench G, Song H, Ramus SJ, Notaridou M, Lawrenson K, Widschwendter M, Vierkant RA, Larson MC, Kjaer SK et al..  2010.  A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.. Nature genetics. 42(10):874-9. Abstract
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Cramer DW, Bast RC, Berg CD, Diamandis EP, Godwin AK, Hartge P, Lokshin AE, Lu KH, McIntosh MW, Mor G et al..  2011.  Ovarian cancer biomarker performance in prostate, lung, colorectal, and ovarian cancer screening trial specimens.. Cancer prevention research (Philadelphia, Pa.). 4(3):365-74. Abstract
Couch FJ, Kuchenbaecker KB, Michailidou K, Mendoza-Fandino GA, Nord S, Lilyquist J, Olswold C, Hallberg E, Agata S, Ahsan H et al..  2016.  Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer.. Nature communications. 7:11375. Abstract
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Bojesen SE, Pooley KA, Johnatty SE, Beesley J, Michailidou K, Tyrer JP, Edwards SL, Pickett HA, Shen HC, Smart CE et al..  2013.  Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.. Nature genetics. 45(4):371-84,384e1-2. Abstract
Bendoraite A, Knouf EC, Garg KS, Parkin RK, Kroh EM, O'Briant KC, Ventura AP, Godwin AK, Karlan BY, Drescher CW et al..  2010.  Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition.. Gynecologic oncology. 116(1):117-25. Abstract