Center-Authored Papers

Filters: Author is Houghton, A McGarry  [Clear All Filters]
2014
Tsuji T, Kelly NJ, Takahashi S, Leme AS, Houghton MGA, Shapiro SD.  2014.  Macrophage Elastase Suppresses White Adipose Tissue Expansion with Cigarette Smoking.. American journal of respiratory cell and molecular biology. Abstract
2015
Gregory AD, Kliment CR, Metz HE, Kim K-H, Kargl J, Agostini BA, Crum LT, Oczypok EA, Oury TA, Houghton MGA.  2015.  Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis.. Journal of leukocyte biology. Abstract
Hidvegi T, Stolz DB, Alcorn JF, Yousem SA, Wang J, Leme AS, Houghton MGA, Hale P, Ewing M, Cai H et al..  2015.  Enhancing autophagy with drugs or lung-directed gene therapy reverses the pathological effects of respiratory epithelial cell proteinopathy.. The Journal of biological chemistry. Abstract
2016
Metz HE, Kargl J, Busch SE, Kim K-H, Kurland BF, Abberbock SR, Randolph-Habecker J, Knoblaugh SE, Kolls JK, White MF et al..  2016.  Insulin receptor substrate-1 deficiency drives a proinflammatory phenotype in KRAS mutant lung adenocarcinoma.. Proceedings of the National Academy of Sciences of the United States of America. 113(31):8795-8800. Abstract
Busch SE, Hanke ML, Kargl J, Metz HE, MacPherson D, Houghton MGA.  2016.  Lung Cancer Subtypes Generate Unique Immune Responses.. Journal of immunology (Baltimore, Md. : 1950). 197(11):4493-4503. Abstract
2017
Manicone AM, Gharib SA, Gong K-Q, Eddy WE, Long ME, Frevert CW, Altemeier WA, Parks WC, Houghton MGA.  2017.  Matrix Metalloproteinase-28 Is a Key Contributor to Emphysema Pathogenesis.. The American journal of pathology. Abstract
Amankulor NM, Kim Y, Arora S, Kargl J, Szulzewsky F, Hanke M, Margineantu DH, Rao A, Bolouri H, Delrow J et al..  2017.  Mutant IDH1 regulates the tumor-associated immune system in gliomas.. Genes & development. 31(8):774-786. Abstract
Roh-Johnson M, Shah AN, Stonick JA, Poudel KR, Kargl J, Yang GH, di Martino J, Hernandez RE, Gast CE, Zarour LR et al..  2017.  Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo.. Developmental cell. 43(5):549-562.e6. Abstract
Kargl J, Busch SE, Yang GHY, Kim K-H, Hanke ML, Metz HE, Hubbard JJ, Lee SM, Madtes DK, McIntosh MW et al..  2017.  Neutrophils dominate the immune cell composition in non-small cell lung cancer.. Nature communications. 8:14381. Abstract
2018
Veatch JR, Lee SM, Fitzgibbon M, Chow I-T, Jesernig B, Schmitt T, Kong YY, Kargl J, Houghton MGA, Thompson JA et al..  2018.  Tumor-infiltrating BRAFV600E-specific CD4+ T cells correlated with complete clinical response in melanoma.. The Journal of clinical investigation. 128(4):1563-1568. Abstract
Mark NM, Kargl J, Busch SE, Yang GHY, Metz HE, Zhang H, Hubbard JJ, Pipavath SNJ, Madtes DK, Houghton MGA.  2018.  Chronic Obstructive Pulmonary Disease Alters Immune Cell Composition and Immune Checkpoint Inhibitor Efficacy in Non-Small Cell Lung Cancer.. American journal of respiratory and critical care medicine. 197(3):325-336. Abstract
2019
Veatch JR, Jesernig BL, Kargl J, Fitzgibbon M, Lee SM, Baik C, Martins R, Houghton MGA, Riddell SR.  2019.  Endogenous CD4 T Cells Recognize Neoantigens in Lung Cancer Patients, Including Recurrent Oncogenic and () Driver Mutations.. Cancer immunology research. 7(6):910-922. Abstract