Center-Authored Papers

Filters: Author is Schiffer, Joshua T  [Clear All Filters]
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2009
Schiffer JT, Kirby K, Sandmaier BM, Storb R, Corey L, Boeckh MJ.  2009.  Timing and severity of community acquired respiratory virus infections after myeloablative versus non-myeloablative hematopoietic stem cell transplantation.. Haematologica. 94(8):1101-8. Abstract
Schiffer JT, Corey L.  2009.  New concepts in understanding genital herpes.. Current infectious disease reports. 11(6):457-64. Abstract
Schiffer JT, Abu-Raddad L, Mark KE, Zhu J, Selke S, Magaret AS, Wald A, Corey L.  2009.  Frequent release of low amounts of herpes simplex virus from neurons: results of a mathematical model.. Science translational medicine. 1(7):7ra16. Abstract
2010
Schiffer JT, Abu-Raddad L, Mark KE, Zhu J, Selke S, Koelle DM, Wald A, Corey L.  2010.  Mucosal host immune response predicts the severity and duration of herpes simplex virus-2 genital tract shedding episodes.. Proceedings of the National Academy of Sciences of the United States of America. 107(44):18973-8. Abstract
Alsallaq RA, Schiffer JT, Longini IM, Wald A, Corey L, Abu-Raddad LJ.  2010.  Population level impact of an imperfect prophylactic vaccine for herpes simplex virus-2.. Sexually transmitted diseases. 37(5):290-7. Abstract
2011
Schiffer JT, Wald A, Selke S, Corey L, Magaret AS.  2011.  The kinetics of mucosal herpes simplex virus-2 infection in humans: evidence for rapid viral-host interactions.. The Journal of infectious diseases. 204(4):554-61. Abstract
Schiffer JT, Scott J, Corey L.  2011.  A siege of hepatitis: fighting a defiant virus.. Nature medicine. 17(3):253-4.
Schiffer JT, Magaret AS, Selke S, Corey L, Wald A.  2011.  Detailed analysis of mucosal herpes simplex virus-2 replication kinetics with and without antiviral therapy.. The Journal of antimicrobial chemotherapy. 66(11):2593-600. Abstract
2012
Schiffer JT, Aubert M, Weber N, Mintzer E, Stone D, Jerome KR.  2012.  Targeted DNA mutagenesis for the cure of chronic viral infections.. Journal of virology. 86(17):8920-36. Abstract
Johnston C, Saracino M, Kuntz S, Magaret AS, Selke S, Huang M-L, Schiffer JT, Koelle DM, Corey L, Wald A.  2012.  Standard-dose and high-dose daily antiviral therapy for short episodes of genital HSV-2 reactivation: three randomised, open-label, cross-over trials.. Lancet. 379(9816):641-647. Abstract
Moss NJ, Magaret A, Laing KJ, Kask AS, Wang M, Mark KE, Schiffer JT, Wald A, Koelle DM.  2012.  Peripheral blood CD4 T-cell and pDC reactivity to HSV-2 and pDC number do not correlate with the clinical or virologic severity of recurrent genital herpes.. Journal of virology. 86(18):9952-63. Abstract
Schouten JT, Schiffer JT.  2012.  Equal HIV-1 decay kinetics in HSV-2-infected and HSV-2-uninfected clinical trial participants treated with antiretroviral therapy. Journal of acquired immune deficiency syndromes (1999). 60(1):68-71. Abstract
2013
Schiffer JT, Swan D, Al Sallaq R, Magaret A, Johnston C, Mark KE, Selke S, Ocbamichael N, Kuntz S, Zhu J et al..  2013.  Rapid localized spread and immunologic containment define Herpes simplex virus-2 reactivation in the human genital tract.. eLife. 2:e00288. Abstract
Schiffer JT.  2013.  Mucosal HSV-2 Specific CD8+ T-Cells Represent Containment of Prior Viral Shedding Rather than a Correlate of Future Protection.. Frontiers in immunology. 4:209. Abstract
Schiffer JT, Swan DA, Stone D, Jerome KR.  2013.  Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: a mathematical modeling approach.. PLoS computational biology. 9(7):e1003131. Abstract
Schiffer JT, Corey L.  2013.  Rapid host immune response and viral dynamics in herpes simplex virus-2 infection.. Nature medicine. 19(3):280-8. Abstract
Schiffer JT, Swan DA, Corey L, Wald A.  2013.  Rapid viral expansion and short drug half-life explain the incomplete effectiveness of current herpes simplex virus 2-directed antiviral agents.. Antimicrobial agents and chemotherapy. 57(12):5820-9. Abstract
Jing L, Schiffer JT, Chong TM, Bruckner JJ, Davies HD, Felgner PL, Haas J, Wald A, Verjans GMGM, Koelle DM.  2013.  CD4 T-cell memory responses to viral infections of humans show pronounced immunodominance independent of duration or viral persistence.. Journal of virology. 87(5):2617-27. Abstract
2014
Weber ND, Stone D, Sedlak RH, De Silva Feelixge HS, Roychoudhury P, Schiffer JT, Aubert M, Jerome KR.  2014.  AAV-Mediated Delivery of Zinc Finger Nucleases Targeting Hepatitis B Virus Inhibits Active Replication.. PloS one. 9(5):e97579. Abstract
Schiffer JT, Mayer BT, Fong Y, Swan DA, Wald A.  2014.  Herpes simplex virus-2 transmission probability estimates based on quantity of viral shedding.. Journal of the Royal Society, Interface / the Royal Society. 11(95):20140160. Abstract
Matrajt L, Younan PM, Kiem H-P, Schiffer JT.  2014.  The majority of CD4+ T-cell depletion during acute SHIV89.6P infection occurs in uninfected cells.. Journal of virology. Abstract
Adolescent
Schiffer JT, Kirby K, Sandmaier BM, Storb R, Corey L, Boeckh MJ.  2009.  Timing and severity of community acquired respiratory virus infections after myeloablative versus non-myeloablative hematopoietic stem cell transplantation.. Haematologica. 94(8):1101-8. Abstract
Adult
Schiffer JT, Kirby K, Sandmaier BM, Storb R, Corey L, Boeckh MJ.  2009.  Timing and severity of community acquired respiratory virus infections after myeloablative versus non-myeloablative hematopoietic stem cell transplantation.. Haematologica. 94(8):1101-8. Abstract
Aged
Schiffer JT, Kirby K, Sandmaier BM, Storb R, Corey L, Boeckh MJ.  2009.  Timing and severity of community acquired respiratory virus infections after myeloablative versus non-myeloablative hematopoietic stem cell transplantation.. Haematologica. 94(8):1101-8. Abstract
Antiviral Agents
Schiffer JT, Scott J, Corey L.  2011.  A siege of hepatitis: fighting a defiant virus.. Nature medicine. 17(3):253-4.