Center-Authored Papers

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Young Adult
Nemecek ER, Guthrie KA, Sorror ML, Wood BL, Doney K, Hilger RA, Scott BL, Kovacsovics TJ, Maziarz RT, Woolfrey AE et al..  2011.  Conditioning with treosulfan and fludarabine followed by allogeneic hematopoietic cell transplantation for high-risk hematologic malignancies.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 17(3):341-50. Abstract
Virulence
Arnoldo A, Curak J, Kittanakom S, Chevelev I, Lee VT, Sahebol-Amri M, Koscik B, Ljuma L, Roy PJ, Bedalov A et al..  2008.  Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen.. PLoS genetics. 4(2):e1000005. Abstract
Vidarabine
Nemecek ER, Guthrie KA, Sorror ML, Wood BL, Doney K, Hilger RA, Scott BL, Kovacsovics TJ, Maziarz RT, Woolfrey AE et al..  2011.  Conditioning with treosulfan and fludarabine followed by allogeneic hematopoietic cell transplantation for high-risk hematologic malignancies.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 17(3):341-50. Abstract
Tumor Necrosis Factor-alpha
Van Gool F, Gallí M, Gueydan C, Kruys V, Prevot P-P, Bedalov A, Mostoslavsky R, Alt FW, De Smedt T, Leo O.  2009.  Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner.. Nature medicine. 15(2):206-10. Abstract
Transplantation Conditioning
Nemecek ER, Guthrie KA, Sorror ML, Wood BL, Doney K, Hilger RA, Scott BL, Kovacsovics TJ, Maziarz RT, Woolfrey AE et al..  2011.  Conditioning with treosulfan and fludarabine followed by allogeneic hematopoietic cell transplantation for high-risk hematologic malignancies.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 17(3):341-50. Abstract
Telomere
Newcomb B, Bedalov A.  2009.  Identification of inhibitors of chromatin modifying enzymes using the yeast phenotypic screens.. Methods in molecular biology (Clifton, N.J.). 548:145-60. Abstract
Survival Analysis
Nemecek ER, Guthrie KA, Sorror ML, Wood BL, Doney K, Hilger RA, Scott BL, Kovacsovics TJ, Maziarz RT, Woolfrey AE et al..  2011.  Conditioning with treosulfan and fludarabine followed by allogeneic hematopoietic cell transplantation for high-risk hematologic malignancies.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 17(3):341-50. Abstract
Small Molecule Libraries
Chevillet JR, Park GJ, Bedalov A, Simon JA, Vasioukhin VI.  2008.  Identification and characterization of small-molecule inhibitors of hepsin.. Molecular cancer therapeutics. 7(10):3343-51. Abstract
Shared Resources
Nemecek ER, Guthrie KA, Sorror ML, Wood BL, Doney K, Hilger RA, Scott BL, Kovacsovics TJ, Maziarz RT, Woolfrey AE et al..  2011.  Conditioning with treosulfan and fludarabine followed by allogeneic hematopoietic cell transplantation for high-risk hematologic malignancies.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 17(3):341-50. Abstract
Leko V, Varnum-Finney B, Li H, Gu Y, Flowers D, Nourigat C, Bernstein ID, Bedalov A.  2012.  SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.. Blood. 119(8):1856-1860. Abstract
Foss EJ, Radulovic D, Stirewalt DL, Radich J, Sala-Torra O, Pogosova-Agadjanyan EL, Hengel SM, Loeb KR, Deeg HJ, Meshinchi S et al..  2012.  Proteomic Classification of Acute Leukemias by Alignment-Based Quantitation of LC-MS/MS Data Sets.. Journal of proteome research. 11(10):5005-10. Abstract
Chevillet JR, Park GJ, Bedalov A, Simon JA, Vasioukhin VI.  2008.  Identification and characterization of small-molecule inhibitors of hepsin.. Molecular cancer therapeutics. 7(10):3343-51. Abstract
Serine Endopeptidases
Chevillet JR, Park GJ, Bedalov A, Simon JA, Vasioukhin VI.  2008.  Identification and characterization of small-molecule inhibitors of hepsin.. Molecular cancer therapeutics. 7(10):3343-51. Abstract
September 2013
Tsuchiyama S, Kwan E, Dang W, Bedalov A, Kennedy BK.  2013.  Sirtuins in yeast: phenotypes and tools.. Methods in molecular biology (Clifton, N.J.). 1077:11-37. Abstract
September 2012
Foss EJ, Radulovic D, Stirewalt DL, Radich J, Sala-Torra O, Pogosova-Agadjanyan EL, Hengel SM, Loeb KR, Deeg HJ, Meshinchi S et al..  2012.  Proteomic Classification of Acute Leukemias by Alignment-Based Quantitation of LC-MS/MS Data Sets.. Journal of proteome research. 11(10):5005-10. Abstract
Scientific Imaging Core Facility
Chevillet JR, Park GJ, Bedalov A, Simon JA, Vasioukhin VI.  2008.  Identification and characterization of small-molecule inhibitors of hepsin.. Molecular cancer therapeutics. 7(10):3343-51. Abstract
Wang J, Wegener JE, Huang T-W, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J et al..  2015.  Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.. Nature. 525(7570):552.
Leko V, Park GJ, Lao U, Simon JA, Bedalov A.  2013.  Enterocyte-Specific Inactivation of SIRT1 Reduces Tumor Load in the APC(+/min) Mouse Model.. PloS one. 8(6):e66283. Abstract
Leko V, Varnum-Finney B, Li H, Gu Y, Flowers D, Nourigat C, Bernstein ID, Bedalov A.  2012.  SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.. Blood. 119(8):1856-1860. Abstract
Wang J, Wegener JE, Huang T-W, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J et al..  2015.  Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.. Nature. 521(7552):E1-4.
Saccharomyces cerevisiae
Newcomb B, Bedalov A.  2009.  Identification of inhibitors of chromatin modifying enzymes using the yeast phenotypic screens.. Methods in molecular biology (Clifton, N.J.). 548:145-60. Abstract
Arnoldo A, Curak J, Kittanakom S, Chevelev I, Lee VT, Sahebol-Amri M, Koscik B, Ljuma L, Roy PJ, Bedalov A et al..  2008.  Identification of small molecule inhibitors of Pseudomonas aeruginosa exoenzyme S using a yeast phenotypic screen.. PLoS genetics. 4(2):e1000005. Abstract
Risk Factors
Nemecek ER, Guthrie KA, Sorror ML, Wood BL, Doney K, Hilger RA, Scott BL, Kovacsovics TJ, Maziarz RT, Woolfrey AE et al..  2011.  Conditioning with treosulfan and fludarabine followed by allogeneic hematopoietic cell transplantation for high-risk hematologic malignancies.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 17(3):341-50. Abstract
Reverse Transcriptase Polymerase Chain Reaction
Van Gool F, Gallí M, Gueydan C, Kruys V, Prevot P-P, Bedalov A, Mostoslavsky R, Alt FW, De Smedt T, Leo O.  2009.  Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner.. Nature medicine. 15(2):206-10. Abstract
Rett Syndrome
Wang J, Wegener JE, Huang T-W, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J et al..  2015.  Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.. Nature. 521(7552):E1-4.