Center-Authored Papers

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Wang Y, Huang J-W, Castella M, Huntsman DG, Taniguchi T.  2014.  p53 is positively regulated by miR-542-3p.. Cancer research. 74(12):3218-27. Abstract
Wang Y, Huang J-W, Calses P, Kemp CJ, Taniguchi T.  2012.  MiR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition.. Cancer research. Abstract
Wang Y, Huang J-W, Li M, Cavenee WK, Mitchell PS, Zhou X, Tewari M, Furnari FB, Taniguchi T.  2011.  MicroRNA-138 Modulates DNA Damage Response by Repressing Histone H2AX Expression.. Molecular cancer research : MCR. 9(8):1100-11. Abstract
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Swisher EM, Taniguchi T, Karlan BY.  2012.  Molecular scores to predict ovarian cancer outcomes: a worthy goal, but not ready for prime time.. Journal of the National Cancer Institute. 104(9):642-5.
Swisher EM, Sakai W, Karlan BY, Wurz K, Urban ND, Taniguchi T.  2008.  Secondary BRCA1 mutations in BRCA1-mutated ovarian carcinomas with platinum resistance.. Cancer research. 68(8):2581-6. Abstract
Swisher EM, Gonzalez RM, Taniguchi T, Garcia RL, Walsh T, Goff BA, Welcsh P.  2009.  Methylation and protein expression of DNA repair genes: association with chemotherapy exposure and survival in sporadic ovarian and peritoneal carcinomas.. Molecular cancer. 8:48. Abstract
Sakai W, Swisher EM, Jacquemont C, Chandramohan KV, Couch FJ, Langdon SP, Wurz K, Higgins J, Villegas E, Taniguchi T.  2009.  Functional restoration of BRCA2 protein by secondary BRCA2 mutations in BRCA2-mutated ovarian carcinoma.. Cancer research. 69(16):6381-6. Abstract
Sakai W, Swisher EM, Karlan BY, Agarwal MK, Higgins J, Friedman C, Villegas E, Jacquemont C, Farrugia DJ, Couch FJ et al..  2008.  Secondary mutations as a mechanism of cisplatin resistance in BRCA2-mutated cancers.. Nature. 451(7182):1116-20. Abstract
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Pennington KP, Wickramanayake A, Norquist BM, Pennil CC, Garcia RL, Agnew KJ, Taniguchi T, Welcsh P, Swisher EM.  2013.  53BP1 expression in sporadic and inherited ovarian carcinoma: Relationship to genetic status and clinical outcomes.. Gynecologic oncology. 128(3):493-9. Abstract
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Norquist B, Wurz KA, Pennil CC, Garcia R, Gross J, Sakai W, Karlan BY, Taniguchi T, Swisher EM.  2011.  Secondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 29(22):3008-15. Abstract
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Konstantinopoulos PA, Spentzos D, Karlan BY, Taniguchi T, Fountzilas E, Francoeur N, Levine DA, Cannistra SA.  2010.  Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 28(22):3555-61. Abstract
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Jacquemont C, Simon JA, D'Andrea AD, Taniguchi T.  2012.  Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin.. Molecular cancer. 11(1):26. Abstract
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Huang J-W, Wang Y, Dhillon KK, Calses P, Villegas E, Mitchell PS, Tewari M, Kemp CJ, Taniguchi T.  2013.  Systematic Screen Identifies miRNAs that Target RAD51 and RAD51D to Enhance Chemosensitivity.. Molecular cancer research : MCR. 11(12):1564-73. Abstract
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Drost R, Dhillon KK, van der Gulden H, van der Heijden I, Brandsma I, Cruz C, Chondronasiou D, Castroviejo-Bermejo M, Boon U, Schut E et al..  2016.  BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1.. The Journal of clinical investigation. 126(8):2903-18. Abstract
Dhillon KK, Swisher EM, Taniguchi T.  2011.  Secondary mutations of BRCA1/2 and drug resistance.. Cancer science. 102(4):663-9. Abstract
Dhillon KK, Bajrami I, Taniguchi T, Lord C.  2016.  Synthetic lethality: the road to novel therapies for breast cancer.. Endocrine-related cancer. 23(10):T39-T55. Abstract
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Cheung RS, Taniguchi T.  2017.  Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers.. International journal of hematology. Abstract
Cheung RS, Castella M, Abeyta A, Gafken PR, Tucker N, Taniguchi T.  2017.  Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex.. Cell reports. 19(12):2432-2440. Abstract
Chen D-H, Below JE, Shimamura A, Keel SB, Matsushita M, Wolff J, Sul Y, Bonkowski E, Castella M, Taniguchi T et al..  2016.  Ataxia-Pancytopenia Syndrome Is Caused by Missense Mutations in SAMD9L.. American journal of human genetics. 98(6):1146-58. Abstract
Castella M, Jacquemont C, Thompson EL, Yeo JE, Cheung RS, Huang J-W, Sobeck A, Hendrickson EA, Taniguchi T.  2015.  FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2.. PLoS genetics. 11(10):e1005563. Abstract
Calses PC, Dhillon KK, Tucker N, Chi Y, Huang J-W, Kawasumi M, Nghiem P, Wang Y, Clurman BE, Jacquemont C et al..  2017.  DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing.. Cell reports. 19(1):162-174. Abstract
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Abeyta A, Castella M, Jacquemont C, Taniguchi T.  2016.  NEK8 regulates DNA damage-induced RAD51 foci formation and replication fork protection.. Cell cycle (Georgetown, Tex.). Abstract