Center-Authored Papers

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2008
Hahn S.  2008.  Transcriptional regulation. Meeting on regulatory mechanisms in eukaryotic transcription.. EMBO reports. 9(7):612-6.
Larivière L, Seizl M, van Wageningen S, Röther S, van de Pasch L, Feldmann H, Strässer K, Hahn S, Holstege FCP, Cramer P.  2008.  Structure-system correlation identifies a gene regulatory Mediator submodule.. Genes & development. 22(7):872-7. Abstract
Mohibullah N, Hahn S.  2008.  Site-specific cross-linking of TBP in vivo and in vitro reveals a direct functional interaction with the SAGA subunit Spt3.. Genes & development. 22(21):2994-3006. Abstract
2009
Liu Y, Warfield L, Zhang C, Luo J, Allen J, Lang WH, Ranish J, Shokat KM, Hahn S.  2009.  Phosphorylation of the transcription elongation factor Spt5 by yeast Bur1 kinase stimulates recruitment of the PAF complex.. Molecular and cellular biology. 29(17):4852-63. Abstract
2010
Herbig E, Warfield L, Fish L, Fishburn J, Knutson BA, Moorefield B, Pacheco D, Hahn S.  2010.  Mechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domains.. Molecular and cellular biology. 30(10):2376-90. Abstract
Eichner J, Chen H-T, Warfield L, Hahn S.  2010.  Position of the general transcription factor TFIIF within the RNA polymerase II transcription preinitiation complex.. The EMBO journal. 29(4):706-16. Abstract
2011
Knutson BA, Hahn S.  2011.  Yeast Rrn7 and human TAF1B are TFIIB-related RNA polymerase I general transcription factors.. Science (New York, N.Y.). 333(6049):1637-40. Abstract
Hahn S, Young ET.  2011.  Transcriptional Regulation in Saccharomyces cerevisiae: Transcription Factor Regulation and Function, Mechanisms of Initiation, and Roles of Activators and Coactivators.. Genetics. 189(3):705-36. Abstract
Knutson BA, Hahn S.  2011.  Domains of Tra1 important for activator recruitment and transcription coactivator functions of SAGA and NuA4 complexes.. Molecular and cellular biology. 31(4):818-31. Abstract
Brzovic PS, Heikaus CC, Kisselev L, Vernon R, Herbig E, Pacheco D, Warfield L, Littlefield P, Baker D, Klevit RE et al..  2011.  The acidic transcription activator gcn4 binds the mediator subunit gal11/med15 using a simple protein interface forming a fuzzy complex.. Molecular cell. 44(6):942-53. Abstract
2012
Luo J, Hahn S, Ranish J.  2012.  An integrated chemical crosslinking and mass spectrometry approach to study protein complex architecture and function.. Molecular & cellular proteomics : MCP. 119(2):M111.008318. Abstract
Fishburn J, Hahn S.  2012.  Architecture of the yeast RNA polymerase II open complex and regulation of activity by TFIIF.. Molecular and cellular biology. 32(1):25. Abstract
2013
Grünberg S, Hahn S.  2013.  Structural insights into transcription initiation by RNA polymerase II.. Trends in biochemical sciences. 38(12):603-11. Abstract
2014
Kamenova I, Warfield L, Hahn S.  2014.  Mutations on the DNA binding surface of TBP discriminate between yeast TATA and TATA-less gene transcription.. Molecular and cellular biology. 34(15):2929-43. Abstract
Warfield L, Tuttle LM, Pacheco D, Klevit RE, Hahn S.  2014.  A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface.. Proceedings of the National Academy of Sciences of the United States of America. 111(34):E3506-13. Abstract
Han Y, Luo J, Ranish J, Hahn S.  2014.  Architecture of the Saccharomyces cerevisiae SAGA transcription coactivator complex.. The EMBO journal. 33(21):2534-46. Abstract
Knutson BA, Luo J, Ranish J, Hahn S.  2014.  Architecture of the Saccharomyces cerevisiae RNA polymerase I Core Factor complex.. Nature structural & molecular biology. 21(9):810-6. Abstract
261
Grünberg S, Warfield L, Hahn S.  2012.  Architecture of the RNA polymerase II preinitiation complex and mechanism of ATP-dependent promoter opening.. Nature structural & molecular biology. Abstract
Adaptor Proteins, Signal Transducing
Knutson BA, Hahn S.  2011.  Domains of Tra1 important for activator recruitment and transcription coactivator functions of SAGA and NuA4 complexes.. Molecular and cellular biology. 31(4):818-31. Abstract
Adenosine Triphosphatases
Mohibullah N, Hahn S.  2008.  Site-specific cross-linking of TBP in vivo and in vitro reveals a direct functional interaction with the SAGA subunit Spt3.. Genes & development. 22(21):2994-3006. Abstract
Alcohol Oxidoreductases
Fishburn J, Hahn S.  2012.  Architecture of the yeast RNA polymerase II open complex and regulation of activity by TFIIF.. Molecular and cellular biology. 32(1):25. Abstract
Amino Acid Sequence
Knutson BA, Hahn S.  2011.  Yeast Rrn7 and human TAF1B are TFIIB-related RNA polymerase I general transcription factors.. Science (New York, N.Y.). 333(6049):1637-40. Abstract
Amino Acid Substitution
Knutson BA, Hahn S.  2011.  Domains of Tra1 important for activator recruitment and transcription coactivator functions of SAGA and NuA4 complexes.. Molecular and cellular biology. 31(4):818-31. Abstract
Knutson BA, Hahn S.  2011.  Yeast Rrn7 and human TAF1B are TFIIB-related RNA polymerase I general transcription factors.. Science (New York, N.Y.). 333(6049):1637-40. Abstract
Aminohydrolases
Fishburn J, Hahn S.  2012.  Architecture of the yeast RNA polymerase II open complex and regulation of activity by TFIIF.. Molecular and cellular biology. 32(1):25. Abstract