Center-Authored Papers

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Niyonzima N, Lambert AR, Werther R, De Silva Feelixge H, Roychoudhury P, Greninger AL, Stone D, Stoddard BL, Jerome KR.  2017.  Tuning DNA binding affinity and cleavage specificity of an engineered gene-targeting nuclease via surface display, flow cytometry and cellular analyses.. Protein engineering, design & selection : PEDS. 30(7):503-522. Abstract
Stone D, Kiem H-P, Jerome KR.  2013.  Targeted gene disruption to cure HIV.. Current opinion in HIV and AIDS. 8(3):217-23. Abstract
Schiffer JT, Aubert M, Weber N, Mintzer E, Stone D, Jerome KR.  2012.  Targeted DNA mutagenesis for the cure of chronic viral infections.. Journal of virology. 86(17):8920-36. Abstract
Weber ND, Stone D, Jerome KR.  2013.  TALENs targeting HBV: designer endonuclease therapies for viral infections.. Molecular therapy : the journal of the American Society of Gene Therapy. 21(10):1819-20.
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Schiffer JT, Swan DA, Stone D, Jerome KR.  2013.  Predictors of hepatitis B cure using gene therapy to deliver DNA cleavage enzymes: a mathematical modeling approach.. PLoS computational biology. 9(7):e1003131. Abstract
Roychoudhury P, De Silva Feelixge HS, Pietz HL, Stone D, Jerome KR, Schiffer JT.  2016.  Pharmacodynamics of anti-HIV gene therapy using viral vectors and targeted endonucleases.. The Journal of antimicrobial chemotherapy. Abstract
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Dang CH, Aubert M, De Silva Feelixge HS, Diem K, Loprieno MA, Roychoudhury P, Stone D, Jerome KR.  2017.  In vivo dynamics of AAV-mediated gene delivery to sensory neurons of the trigeminal ganglia.. Scientific reports. 7(1):927. Abstract
Aubert M, Madden EA, Loprieno M, De Silva Feelixge HS, Stensland L, Huang M-L, Greninger AL, Roychoudhury P, Niyonzima N, Nguyen T et al..  2016.  In vivo disruption of latent HSV by designer endonuclease therapy.. JCI insight. 1(14) Abstract
Aubert M, Boyle NM, Stone D, Stensland L, Huang M-L, Magaret AS, Galetto R, Rawlings DJ, Scharenberg AM, Jerome KR.  2014.  In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease.. Molecular therapy. Nucleic acids. 3:e146. Abstract
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Stone D, Niyonzima N, Jerome KR.  2016.  Genome editing and the next generation of antiviral therapy.. Human genetics. Abstract
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Weber ND, Aubert M, Dang CH, Stone D, Jerome KR.  2014.  DNA cleavage enzymes for treatment of persistent viral infections: Recent advances and the pathway forward.. Virology. 454-455(353-61) Abstract
Sedlak RH, Liang S, Niyonzima N, De Silva Feelixge HS, Roychoudhury P, Greninger AL, Weber ND, Boissel S, Scharenberg AM, Cheng A et al..  2016.  Digital detection of endonuclease mediated gene disruption in the HIV provirus.. Scientific reports. 6:20064. Abstract
De Silva Feelixge HS, Stone D, Pietz HL, Roychoudhury P, Greninger AL, Schiffer JT, Aubert M, Jerome KR.  2015.  Detection of treatment-resistant infectious HIV after genome-directed antiviral endonuclease therapy.. Antiviral research. Abstract
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Weber ND, Stone D, Sedlak RH, De Silva Feelixge HS, Roychoudhury P, Schiffer JT, Aubert M, Jerome KR.  2014.  AAV-Mediated Delivery of Zinc Finger Nucleases Targeting Hepatitis B Virus Inhibits Active Replication.. PloS one. 9(5):e97579. Abstract