Center-Authored Papers

Filters: Author is Greenberg, Philip  [Clear All Filters]
1996
Yee C, Gilbert MJ, Riddell SR, Brichard VG, Fefer A, Thompson JA, Boon T, Greenberg PD.  1996.  Isolation of tyrosinase-specific CD8+ and CD4+ T cell clones from the peripheral blood of melanoma patients following in vitro stimulation with recombinant vaccinia virus.. Journal of immunology (Baltimore, Md. : 1950). 157(9):4079-86. Abstract
1999
Yee C, Savage PA, Lee PP, Davis MM, Greenberg PD.  1999.  Isolation of high avidity melanoma-reactive CTL from heterogeneous populations using peptide-MHC tetramers.. Journal of immunology (Baltimore, Md. : 1950). 162(4):2227-34. Abstract
Lee PP, Yee C, Savage PA, Fong L, Brockstedt D, Weber JS, Johnson D, Swetter S, Thompson J, Greenberg PD et al..  1999.  Characterization of circulating T cells specific for tumor-associated antigens in melanoma patients.. Nature medicine. 5(6):677-85. Abstract
2002
Yee C, Thompson JA, Byrd D, Riddell SR, Roche P, Celis E, Greenberg PD.  2002.  Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma: in vivo persistence, migration, and antitumor effect of transferred T cells.. Proceedings of the National Academy of Sciences of the United States of America. 99(25):16168-73. Abstract
Yee C, Greenberg P.  2002.  Modulating T-cell immunity to tumours: new strategies for monitoring T-cell responses.. Nature reviews. Cancer. 2(6):409-19.
2004
Wang J, Press OW, Lindgren CG, Greenberg P, Riddell S, Qian X, Laugen C, Raubitschek A, Forman SJ, Jensen MC.  2004.  Cellular immunotherapy for follicular lymphoma using genetically modified CD20-specific CD8+ cytotoxic T lymphocytes.. Molecular therapy : the journal of the American Society of Gene Therapy. 9(4):577-86. Abstract
Liao X, Li Y, Bonini C, Nair S, Gilboa E, Greenberg PD, Yee C.  2004.  Transfection of RNA encoding tumor antigens following maturation of dendritic cells leads to prolonged presentation of antigen and the generation of high-affinity tumor-reactive cytotoxic T lymphocytes.. Molecular therapy : the journal of the American Society of Gene Therapy. 9(5):757-64. Abstract
2007
Wang J, Jensen M, Lin Y, Sui X, Chen E, Lindgren CG, Till B, Raubitschek A, Forman SJ, Qian X et al..  2007.  Optimizing adoptive polyclonal T cell immunotherapy of lymphomas, using a chimeric T cell receptor possessing CD28 and CD137 costimulatory domains.. Human gene therapy. 18(8):712-25. Abstract
2008
Teague RM, Greenberg PD, Fowler C, Huang MZ, Tan X, Morimoto J, Dossett ML, Huseby ES, Ohlén C.  2008.  Peripheral CD8+ T cell tolerance to self-proteins is regulated proximally at the T cell receptor.. Immunity. 28(5):662-74. Abstract
James SE, Greenberg PD, Jensen MC, Lin Y, Wang J, Till BG, Raubitschek AA, Forman SJ, Press OW.  2008.  Antigen sensitivity of CD22-specific chimeric TCR is modulated by target epitope distance from the cell membrane.. Journal of immunology (Baltimore, Md. : 1950). 180(10):7028-38. Abstract
Wölfl M, Rutebemberwa A, Mosbruger T, Mao Q, Li H-mei, Netski D, Ray SC, Pardoll D, Sidney J, Sette A et al..  2008.  Hepatitis C virus immune escape via exploitation of a hole in the T cell repertoire.. Journal of immunology (Baltimore, Md. : 1950). 181(9):6435-46. Abstract
Till BG, Jensen MC, Wang J, Chen EY, Wood BL, Greisman HA, Qian X, James SE, Raubitschek A, Forman SJ et al..  2008.  Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells.. Blood. 112(6):2261-71. Abstract
2009
Dossett ML, Teague RM, Schmitt TM, Tan X, Cooper LJ, Pinzon C, Greenberg PD.  2009.  Adoptive immunotherapy of disseminated leukemia with TCR-transduced, CD8+ T cells expressing a known endogenous TCR.. Molecular therapy : the journal of the American Society of Gene Therapy. 17(4):742-9. Abstract
Lee SH, Yun S, Lee J, Kim MJ, Piao Z-H, Jeong M, Chung JW, Kim T-D, Yoon SR, Greenberg PD et al..  2009.  RasGRP1 is required for human NK cell function.. Journal of immunology (Baltimore, Md. : 1950). 183(12):7931-8. Abstract
James SE, Orgun NN, Tedder TF, Shlomchik MJ, Jensen MC, Lin Y, Greenberg PD, Press OW.  2009.  Antibody-mediated B-cell depletion before adoptive immunotherapy with T cells expressing CD20-specific chimeric T-cell receptors facilitates eradication of leukemia in immunocompetent mice.. Blood. 114(27):5454-63. Abstract
Richman SA, Aggen DH, Dossett ML, Donermeyer DL, Allen PM, Greenberg PD, Kranz DM.  2009.  Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain ValphaVbeta fragments.. Molecular immunology. 46(5):902-16. Abstract
Kuball J, Hauptrock B, Malina V, Antunes E, Voss R-H, Wolfl M, Strong RK, Theobald M, Greenberg PD.  2009.  Increasing functional avidity of TCR-redirected T cells by removing defined N-glycosylation sites in the TCR constant domain.. The Journal of experimental medicine. 206(2):463-75. Abstract
Schmitt TM, Ragnarsson GB, Greenberg PD.  2009.  T cell receptor gene therapy for cancer.. Human gene therapy. 20(11):1240-8. Abstract
2010
James SE, Greenberg PD, Jensen MC, Lin Y, Wang J, Budde LE, Till BG, Raubitschek AA, Forman SJ, Press OW.  2010.  Mathematical modeling of chimeric TCR triggering predicts the magnitude of target lysis and its impairment by TCR downmodulation.. Journal of immunology (Baltimore, Md. : 1950). 184(8):4284-94. Abstract
Stromnes IM, Blattman JN, Tan X, Jeevanjee S, Gu H, Greenberg PD.  2010.  Abrogating Cbl-b in effector CD8(+) T cells improves the efficacy of adoptive therapy of leukemia in mice.. The Journal of clinical investigation. 120(10):3722-34. Abstract
Fowler CC, Pao LI, Blattman JN, Greenberg PD.  2010.  SHP-1 in T cells limits the production of CD8 effector cells without impacting the formation of long-lived central memory cells.. Journal of immunology (Baltimore, Md. : 1950). 185(6):3256-67. Abstract
2011
Tan X, Sande JL, Pufnock JS, Blattman JN, Greenberg PD.  2011.  Retinoic acid as a vaccine adjuvant enhances CD8+ T cell response and mucosal protection from viral challenge.. Journal of virology. 85(16):8316-27. Abstract
Greenberg PD.  2011.  Ralph M. Steinman: A man, a microscope, a cell, and so much more.. Proceedings of the National Academy of Sciences of the United States of America. 108(52):20871-2.
Kuball J, de Boer K, Wagner E, Wattad M, Antunes E, Weeratna RD, Vicari AP, Lotz C, van Dorp S, Hol S et al..  2011.  Pitfalls of vaccinations with WT1-, Proteinase3- and MUC1-derived peptides in combination with MontanideISA51 and CpG7909.. Cancer immunology, immunotherapy : CII. 60(2):161-71. Abstract
Pufnock JS, Cigal M, Rolczynski LS, Andersen-Nissen E, Wolfl M, McElrath MJ, Greenberg PD.  2011.  Priming CD8+ T cells with dendritic cells matured using TLR4 and TLR7/8 ligands together enhances generation of CD8+ T cells retaining CD28.. Blood. 117(24):6542-51. Abstract