Center-Authored Papers

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1987
Palmer TD, Hock RA, Osborne WR, Miller AD.  1987.  Efficient retrovirus-mediated transfer and expression of a human adenosine deaminase gene in diploid skin fibroblasts from an adenosine deaminase-deficient human.. Proceedings of the National Academy of Sciences of the United States of America. 84(4):1055-9. Abstract
1988
Osborne WR, Miller AD.  1988.  Design of vectors for efficient expression of human purine nucleoside phosphorylase in skin fibroblasts from enzyme-deficient humans.. Proceedings of the National Academy of Sciences of the United States of America. 85(18):6851-5. Abstract
1989
Hock RA, Miller AD, Osborne WR.  1989.  Expression of human adenosine deaminase from various strong promoters after gene transfer into human hematopoietic cell lines.. Blood. 74(2):876-81. Abstract
1990
Osborne WR, Hock RA, Kaleko M, Miller AD.  1990.  Long-term expression of human adenosine deaminase in mice after transplantation of bone marrow infected with amphotropic retroviral vectors.. Human gene therapy. 1(1):31-41. Abstract
Kaleko M, Garcia JV, Osborne WR, Miller AD.  1990.  Expression of human adenosine deaminase in mice after transplantation of genetically-modified bone marrow.. Blood. 75(8):1733-41. Abstract
1991
Stockschlaeder MA, Storb R, Osborne WR, Miller AD.  1991.  L-histidinol provides effective selection of retrovirus-vector-transduced keratinocytes without impairing their proliferative potential.. Human gene therapy. 2(1):33-9. Abstract
Palmer TD, Rosman GJ, Osborne WR, Miller AD.  1991.  Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes.. Proceedings of the National Academy of Sciences of the United States of America. 88(4):1330-4. Abstract
Adam MA, Ramesh N, Miller AD, Osborne WR.  1991.  Internal initiation of translation in retroviral vectors carrying picornavirus 5' nontranslated regions.. Journal of virology. 65(9):4985-90. Abstract
Culver KW, Osborne WR, Miller AD, Fleisher TA, Berger M, Anderson WF, Blaese RM.  1991.  Correction of ADA deficiency in human T lymphocytes using retroviral-mediated gene transfer.. Transplantation proceedings. 23(1 Pt 1):170-1.
1992
Lynch CM, Clowes MM, Osborne WR, Clowes AW, Miller AD.  1992.  Long-term expression of human adenosine deaminase in vascular smooth muscle cells of rats: a model for gene therapy.. Proceedings of the National Academy of Sciences of the United States of America. 89(3):1138-42. Abstract
1994
Clowes MM, Lynch CM, Miller AD, Miller DG, Osborne WR, Clowes AW.  1994.  Long-term biological response of injured rat carotid artery seeded with smooth muscle cells expressing retrovirally introduced human genes.. The Journal of clinical investigation. 93(2):644-51. Abstract
1995
Adam MA, Osborne WR, Miller AD.  1995.  R-region cDNA inserts in retroviral vectors are compatible with virus replication and high-level protein synthesis from the insert.. Human gene therapy. 6(9):1169-76. Abstract
Adenosine
Palmer TD, Hock RA, Osborne WR, Miller AD.  1987.  Efficient retrovirus-mediated transfer and expression of a human adenosine deaminase gene in diploid skin fibroblasts from an adenosine deaminase-deficient human.. Proceedings of the National Academy of Sciences of the United States of America. 84(4):1055-9. Abstract
Adenosine Deaminase
Lynch CM, Clowes MM, Osborne WR, Clowes AW, Miller AD.  1992.  Long-term expression of human adenosine deaminase in vascular smooth muscle cells of rats: a model for gene therapy.. Proceedings of the National Academy of Sciences of the United States of America. 89(3):1138-42. Abstract
Kaleko M, Garcia JV, Osborne WR, Miller AD.  1990.  Expression of human adenosine deaminase in mice after transplantation of genetically-modified bone marrow.. Blood. 75(8):1733-41. Abstract
Culver KW, Osborne WR, Miller AD, Fleisher TA, Berger M, Anderson WF, Blaese RM.  1991.  Correction of ADA deficiency in human T lymphocytes using retroviral-mediated gene transfer.. Transplantation proceedings. 23(1 Pt 1):170-1.
Hock RA, Miller AD, Osborne WR.  1989.  Expression of human adenosine deaminase from various strong promoters after gene transfer into human hematopoietic cell lines.. Blood. 74(2):876-81. Abstract
Clowes MM, Lynch CM, Miller AD, Miller DG, Osborne WR, Clowes AW.  1994.  Long-term biological response of injured rat carotid artery seeded with smooth muscle cells expressing retrovirally introduced human genes.. The Journal of clinical investigation. 93(2):644-51. Abstract
Palmer TD, Rosman GJ, Osborne WR, Miller AD.  1991.  Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes.. Proceedings of the National Academy of Sciences of the United States of America. 88(4):1330-4. Abstract
Palmer TD, Hock RA, Osborne WR, Miller AD.  1987.  Efficient retrovirus-mediated transfer and expression of a human adenosine deaminase gene in diploid skin fibroblasts from an adenosine deaminase-deficient human.. Proceedings of the National Academy of Sciences of the United States of America. 84(4):1055-9. Abstract
Stockschlaeder MA, Storb R, Osborne WR, Miller AD.  1991.  L-histidinol provides effective selection of retrovirus-vector-transduced keratinocytes without impairing their proliferative potential.. Human gene therapy. 2(1):33-9. Abstract
Osborne WR, Hock RA, Kaleko M, Miller AD.  1990.  Long-term expression of human adenosine deaminase in mice after transplantation of bone marrow infected with amphotropic retroviral vectors.. Human gene therapy. 1(1):31-41. Abstract
Adam MA, Ramesh N, Miller AD, Osborne WR.  1991.  Internal initiation of translation in retroviral vectors carrying picornavirus 5' nontranslated regions.. Journal of virology. 65(9):4985-90. Abstract
Alcohol Oxidoreductases
Stockschlaeder MA, Storb R, Osborne WR, Miller AD.  1991.  L-histidinol provides effective selection of retrovirus-vector-transduced keratinocytes without impairing their proliferative potential.. Human gene therapy. 2(1):33-9. Abstract
Alkaline Phosphatase
Clowes MM, Lynch CM, Miller AD, Miller DG, Osborne WR, Clowes AW.  1994.  Long-term biological response of injured rat carotid artery seeded with smooth muscle cells expressing retrovirally introduced human genes.. The Journal of clinical investigation. 93(2):644-51. Abstract