Center-Authored Papers

Filters: Author is Kiem, H P  [Clear All Filters]
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Adair JE, Waters T, Haworth KG, Kubek SP, Trobridge GD, Hocum JD, Heimfeld S, Kiem H-P.  2016.  Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy.. Nature communications. 7:13173. Abstract
Adair JE, Johnston SK, Mrugala MM, Beard BC, Guyman LA, Baldock AL, Bridge CA, Hawkins-Daarud A, Gori JL, Born DE et al..  2014.  Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients.. The Journal of clinical investigation. 124(9):4082-92. Abstract
Adair JE, Zhao X, Chien S, Fang M, Wohlfahrt ME, Trobridge GD, Taylor JA, Beard BC, Kiem H-P, Becker PS.  2012.  Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities.. Journal of molecular medicine (Berlin, Germany). 90(11):1283-1294. Abstract
Adair JE, Beard BC, Trobridge GD, Neff T, Rockhill JK, Silbergeld DL, Mrugala MM, Kiem H-P.  2012.  Extended Survival of Glioblastoma Patients After Chemoprotective HSC Gene Therapy.. Science translational medicine. 4(133):133ra57. Abstract
Adair JE, Chandrasekaran D, Sghia-Hughes G, Haworth KG, Woolfrey AE, Burroughs LM, Choi GY, Becker PS, Kiem H-P.  2018.  Novel lineage depletion preserves autologous blood stem cells for gene therapy of Fanconi anemia complementation group A.. Haematologica. Abstract
Andrews RG, Peterson LJ, Morris J, Potter J, Heyward S, Gough M, Bryant E, Kiem HP.  2000.  Differential engraftment of genetically modified CD34(+) and CD34(-) hematopoietic cell subsets in lethally irradiated baboons.. Experimental hematology. 28(5):508-18. Abstract
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Beard BC, Sud R, Keyser KA, Ironside C, Neff T, Gerull S, Trobridge GD, Kiem H-P.  2009.  Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients.. Blood. 113(21):5094-103. Abstract
Beard BC, Trobridge GD, Ironside C, McCune JS, Adair JE, Kiem H-P.  2010.  Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates.. The Journal of clinical investigation. 120(7):2345-54. Abstract
Beard BC, Kiem H-P.  2009.  Canine models of gene-modified hematopoiesis.. Methods in molecular biology (Clifton, N.J.). 506:341-61. Abstract
Beard BC, Adair JE, Trobridge GD, Kiem H-P.  2014.  High-throughput genomic mapping of vector integration sites in gene therapy studies.. Methods in molecular biology (Clifton, N.J.). 1185:321-44. Abstract
Becker PS, Taylor JA, Trobridge GD, Zhao X, Beard BC, Chien S, Adair J, Kohn DB, Wagner JE, Shimamura A et al..  2010.  Preclinical correction of human Fanconi anemia complementation group A bone marrow cells using a safety-modified lentiviral vector.. Gene therapy. 17(10):1244-52. Abstract
Berger C, Berger M, Beard BC, Kiem H-P, Gooley TA, Riddell SR.  2013.  Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques.. PloS one. 8(2):e56268. Abstract
Bonfim C, Ribeiro L, Nichele S, Loth G, Bitencourt M, Koliski A, Kuwahara C, Fabro AL, Pereira NF, Pilonetto D et al..  2016.  Haploidentical Bone Marrow Transplantation with Post-Transplant Cyclophosphamide for Children and Adolescents with Fanconi Anemia.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. Abstract
Bonig H, Priestley GV, Wohlfahrt M, Kiem H-P, Papayannopoulou T.  2009.  Blockade of alpha6-integrin reveals diversity in homing patterns among human, baboon, and murine cells.. Stem cells and development. 18(6):839-44. Abstract
Bonig H, Watts KL, Chang K-H, Kiem H-P, Papayannopoulou T.  2009.  Concurrent blockade of alpha4-integrin and CXCR4 in hematopoietic stem/progenitor cell mobilization.. Stem cells (Dayton, Ohio). 27(4):836-7. Abstract
Burtner CR, Beard BC, Kennedy DR, Wohlfahrt ME, Adair JE, Trobridge GD, Scharenberg AM, Torgerson TR, Rawlings DJ, Felsburg PJ et al..  2014.  Intravenous injection of a foamy virus vector to correct canine SCID-X1.. Blood. 123(23):3578-84. Abstract
Burtner C, Chandrasekaran D, Santos E, Beard B, Adair J, Hamlin D, Wilbur SD, Sandmaier B, Kiem H-P.  2015.  211Astatine-conjugated monoclonal CD45 antibody-based nonmyeloablative conditioning for stem cell gene therapy.. Human gene therapy. Abstract
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Cannon PM, Kohn DB, Kiem H-P.  2014.  HIV eradication-from Berlin to Boston.. Nature biotechnology. 32(4):315-6.
Carnevale-Schianca F, Leisenring WM, Martin PJ, Furlong T, Schoch G, Anasetti C, Appelbaum FR, Carpenter PA, Deeg HJ, Kiem H-P et al..  2009.  Longitudinal assessment of morbidity and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation: retrospective analysis of a multicenter phase III study.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 15(6):749-56. Abstract
Certo MT, Gwiazda KS, Kuhar R, Sather B, Curinga G, Mandt T, Brault M, Lambert AR, Baxter SK, Jacoby K et al..  2012.  Coupling endonucleases with DNA end-processing enzymes to drive gene disruption.. Nature methods. 9(10):973-5. Abstract
Chandrasekaran D, Nakamoto B, Watts KL, Kiem H-P, Papayannopoulou T.  2014.  Modeling promising nonmyeloablative conditioning regimens in nonhuman primates.. Human gene therapy. Abstract
Chong JJ, Yang X, Don CW, Minami E, Liu Y-W, Weyers JJ, Mahoney WM, Van Biber B, Palpant NJ, Gantz JA et al..  2014.  Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.. Nature. Abstract
Corrigan-Curay J, Cohen-Haguenauer O, O'Reilly M, Ross SR, Fan H, Rosenberg N, Somia N, King N, Friedmann T, Dunbar C et al..  2012.  Challenges in vector and trial design using retroviral vectors for long-term gene correction in hematopoietic stem cell gene therapy.. Molecular therapy : the journal of the American Society of Gene Therapy. 20(6):1084-94.
Corrigan-Curay J, Kiem H-P, Baltimore D, O'Reilly M, Brentjens RJ, Cooper L, Forman S, Gottschalk S, Greenberg P, Junghans R et al..  2014.  T-cell immunotherapy: looking forward.. Molecular therapy : the journal of the American Society of Gene Therapy. 22(9):1564-74.
Cowan MJ, Kiem H-P.  2016.  Devouring the Hematopoietic Stem Cell: Setting the Table for Marrow Cell Transplantation.. Molecular therapy : the journal of the American Society of Gene Therapy. 24(11):1892-1894.