Center-Authored Papers

Filters: Author is Bradley, Robert K  [Clear All Filters]
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 
W
Fei DL, Motowski H, Chatrikhi R, Prasad S, Yu J, Gao S, Kielkopf CL, Bradley RK, Varmus H.  2016.  Wild-Type U2AF1 Antagonizes the Splicing Program Characteristic of U2AF1-Mutant Tumors and Is Required for Cell Survival.. PLoS genetics. 12(10):e1006384. Abstract
Dvinge H, Bradley RK.  2015.  Widespread intron retention diversifies most cancer transcriptomes.. Genome medicine. 7(1):45. Abstract
U
Ilagan JO, Ramakrishnan A, Hayes B, Murphy ME, Zebari AS, Bradley P, Bradley RK.  2015.  U2AF1 mutations alter splice site recognition in hematological malignancies.. Genome research. 25(1):14-26. Abstract
T
Jagannathan S, Bradley RK.  2016.  Translational plasticity facilitates the accumulation of nonsense genetic variants in the human population.. Genome research. Abstract
Satija R, Bradley RK.  2012.  The TAGteam motif facilitates binding of 21 sequence-specific transcription factors in the Drosophila embryo.. Genome research. 22(4):656-665. Abstract
S
Kim E, Ilagan JO, Liang Y, Daubner GM, Lee SC-W, Ramakrishnan A, Li Y, Chung YR, Micol J-B, Murphy ME et al..  2015.  SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition.. Cancer cell. 27(5):617-30. Abstract
Inoue D, Bradley RK, Abdel-Wahab O.  2016.  Spliceosomal gene mutations in myelodysplasia: molecular links to clonal abnormalities of hematopoiesis.. Genes & development. 30(9):989-1001. Abstract
Dvinge H, Ries RE, Ilagan JO, Stirewalt DL, Meshinchi S, Bradley RK.  2014.  Sample processing obscures cancer-specific alterations in leukemic transcriptomes.. Proceedings of the National Academy of Sciences of the United States of America. 111(47):16802-7. Abstract
R
Feng Q, Jagannathan S, Bradley RK.  2017.  The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity.. Molecular cell. Abstract
Dvinge H, Kim E, Abdel-Wahab O, Bradley RK.  2016.  RNA splicing factors as oncoproteins and tumour suppressors.. Nature reviews. Cancer. Abstract
Q
Jagannathan S, Ogata Y, Gafken PR, Tapscott SJ, Bradley RK.  2019.  Quantitative proteomics reveals key roles for post-transcriptional gene regulation in the molecular pathology of FSHD.. eLife. 8 Abstract
M
Lee SC-W, Dvinge H, Kim E, Cho H, Micol J-B, Chung YR, Durham BH, Yoshimi A, Kim YJ, Thomas M et al..  2016.  Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins.. Nature medicine. 22(6):672-+. Abstract
Jagannathan S, Shadle S, Resnick R, Snider L, Tawil RN, van der Maarel SM, Bradley RK, Tapscott SJ.  2016.  Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells.. Human molecular genetics. Abstract
I
Robinson D, Van Allen EM, Wu Y-M, Schultz N, Lonigro RJ, Mosquera J-M, Montgomery B, Taplin M-E, Pritchard CC, Attard G et al..  2015.  Integrative clinical genomics of advanced prostate cancer.. Cell. 161(5):1215-28. Abstract
H
Xi Z, Bradley RK, Wurdack KJ, Wong KM, Sugumaran M, Bomblies K, Rest JS, Davis CC.  2012.  Horizontal transfer of expressed genes in a parasitic flowering plant.. BMC genomics. 13(1):227. Abstract
G
Hubert CG, Bradley RK, Ding Y, Toledo CM, Herman J, Skutt-Kakaria K, Girard EJ, Davison J, Berndt J, Corrin P et al..  2013.  Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A.. Genes & development. 27(9):1032-45. Abstract
F
Feng Q, Snider L, Jagannathan S, Tawil R, van der Maarel SM, Tapscott SJ, Bradley RK.  2015.  A feedback loop between nonsense-mediated decay and the retrogene DUX4 in facioscapulohumeral muscular dystrophy.. eLife. 4 Abstract
E
Hickey TE, Irvine CM, Dvinge H, Tarulli GA, Hanson AR, Ryan NK, Pickering MA, Birrell SN, Hu DG, Mackenzie PI et al..  2015.  Expression of androgen receptor splice variants in clinical breast cancers.. Oncotarget. Abstract
C
Jagannathan S, Bradley RK.  2017.  Congenital myotonic dystrophy-an RNA-mediated disease across a developmental continuum.. Genes & development. 31(11):1067-1068. Abstract
A
Bradley RK, Merkin J, Lambert NJ, Burge CB.  2012.  Alternative splicing of RNA triplets is often regulated and accelerates proteome evolution.. PLoS biology. 10(1):e1001229. Abstract