Center-Authored Papers

Filters: Author is Tapscott, Stephen J  [Clear All Filters]
Journal Article
Parker MH, Loretz C, Tyler AE, Duddy WJ, Hall JK, Olwin BB, Bernstein ID, Storb R, Tapscott SJ.  2012.  Activation of Notch Signaling During ex vivo Expansion Maintains Donor Muscle Cell Engraftment.. Stem cells (Dayton, Ohio). Abstract
Wang Z, Storb R, Tapscott SJ, Riddell SR.  2012.  Analyzing Cellular Immunity to AAV in a Canine Model Using ELISPOT Assay.. Methods in molecular biology (Clifton, N.J.). 792:65-74. Abstract
Guenthoer J, Diede SJ, Tanaka H, Chai X, Hsu L, Tapscott SJ, Porter PL.  2012.  Assessment of palindromes as platforms for DNA amplification in breast cancer.. Genome research. 22(2):232-45. Abstract
Campbell AE, Oliva J, Yates MP, Zhong JW, Shadle SC, Snider L, Singh N, Tai S, Hiramuki Y, Tawil R et al..  2017.  BET bromodomain inhibitors and agonists of the beta-2 adrenergic receptor identified in screens for compounds that inhibit DUX4 expression in FSHD muscle cells.. Skeletal muscle. 7(1):16. Abstract
Kimura E, Han JJ, Li S, Fall B, Ra J, Haraguchi M, Tapscott SJ, Chamberlain JS.  2008.  Cell-lineage regulated myogenesis for dystrophin replacement: a novel therapeutic approach for treatment of muscular dystrophy.. Human molecular genetics. 17(16):2507-17. Abstract
Tawil R, Padberg GW, Shaw DW, van der Maarel SM, Tapscott SJ.  2016.  Clinical trial preparedness in facioscapulohumeral muscular dystrophy: Clinical, tissue, and imaging outcome measures 29-30 May 2015, Rochester, New York.. Neuromuscular disorders : NMD. 26(2):181-186.
Yao Z, Fong AP, Cao Y, Ruzzo WL, Gentleman RC, Tapscott SJ.  2013.  Comparison of endogenous and overexpressed MyoD shows enhanced binding of physiologically bound sites.. Skeletal muscle. 3(1):8. Abstract
MacQuarrie KL, Yao Z, Fong AP, Diede SJ, Rudzinski ER, Hawkins DS, Tapscott SJ.  2013.  Comparison of Genome-Wide Binding of MyoD in Normal Human Myogenic Cells and Rhabdomyosarcomas Identifies Regional and Local Suppression of Promyogenic Transcription Factors.. Molecular and cellular biology. 33(4):773-84. Abstract
Whiddon JL, Langford AT, Wong C-J, Zhong JW, Tapscott SJ.  2017.  Conservation and innovation in the DUX4-family gene network.. Nature genetics. Abstract
Hendrickson PG, Doráis JA, Grow EJ, Whiddon JL, Lim J-W, Wike CL, Weaver BD, Pflueger C, Emery BR, Wilcox AL et al..  2017.  Conserved roles of mouse DUX and human DUX4 in activating cleavage-stage genes and MERVL/HERVL retrotransposons.. Nature genetics. Abstract
Fong AP, Yao Z, Zhong JW, Johnson NM, Farr GH, Maves L, Tapscott SJ.  2015.  Conversion of MyoD to a Neurogenic Factor: Binding Site Specificity Determines Lineage.. Cell reports. 10(12):1937-46. Abstract
Balog J, Thijssen PE, de Greef JC, Shah B, van Engelen BGM, Yokomori K, Tapscott SJ, Tawil R, van der Maarel SM.  2012.  Correlation analysis of clinical parameters with epigenetic modifications in the DUX4 promoter in FSHD.. Epigenetics : official journal of the DNA Methylation Society. 7(6):579-584. Abstract
Libby RT, Hagerman KA, Pineda VV, Lau R, Cho DH, Baccam SL, Axford MM, Cleary JD, Moore JM, Sopher BL et al..  2008.  CTCF cis-regulates trinucleotide repeat instability in an epigenetic manner: a novel basis for mutational hot spot determination.. PLoS genetics. 4(11):e1000257. Abstract
Lim J-W, Snider L, Yao Z, Tawil R, van der Maarel SM, Rigo F, Bennett FC, Filippova GN, Tapscott SJ.  2015.  DICER/AGO-dependent Epigenetic Silencing of D4Z4 Repeats Enhanced by Exogenous siRNA Suggests Mechanisms and Therapies for FSHD.. Human molecular genetics. Abstract
Palii CG, Perez-Iratxeta C, Yao Z, Cao Y, Dai F, Davison J, Atkins H, Allan D, Dilworth JF, Gentleman R et al..  2011.  Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages.. The EMBO journal. 30(3):494-509. Abstract
Lemmers RJLF, Tawil R, Petek LM, Balog J, Block GJ, Santen GWE, Amell AM, van der Vliet PJ, Almomani R, Straasheijm KR et al..  2012.  Digenic inheritance of an SMCHD1 mutation and an FSHD-permissive D4Z4 allele causes facioscapulohumeral muscular dystrophy type 2.. Nature genetics. 44(12):1370-4. Abstract
Yao Z, MacQuarrie KL, Fong AP, Tapscott SJ, Ruzzo WL, Gentleman RC.  2013.  Discriminative motif analysis of high-throughput dataset.. Bioinformatics (Oxford, England). Abstract
Conerly ML, Yao Z, Zhong JW, Groudine M, Tapscott SJ.  2016.  Distinct Activities of Myf5 and MyoD Indicate Separate Roles in Skeletal Muscle Lineage Specification and Differentiation.. Developmental cell. 36(4):375-85. Abstract
Diede SJ, Guenthoer J, Geng LN, Mahoney SE, Marotta M, Olson JM, Tanaka H, Tapscott SJ.  2010.  DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences.. Proceedings of the National Academy of Sciences of the United States of America. 107(1):234-9. Abstract
van den Boogaard ML, Jfl Lemmers R, Camaño P, van der Vliet PJ, Voermans N, van Engelen BGM, Lopez de Munain A, Tapscott SJ, van der Stoep N, Tawil R et al..  2015.  Double SMCHD1 variants in FSHD2: the synergistic effect of two SMCHD1 variants on D4Z4 hypomethylation and disease penetrance in FSHD2.. European journal of human genetics : EJHG. Abstract
Knight MA, Hernandez D, Diede SJ, Dauwerse HG, Rafferty I, van de Leemput J, Forrest SM, Gardner MKRJ, Storey E, van Ommen G-JB et al..  2008.  A duplication at chromosome 11q12.2-11q12.3 is associated with spinocerebellar ataxia type 20.. Human molecular genetics. 17(24):3847-53. Abstract
Geng LN, Yao Z, Snider L, Fong AP, Cech JN, Young JM, van der Maarel SM, Ruzzo WL, Gentleman RC, Tawil R et al..  2012.  DUX4 Activates Germline Genes, Retroelements, and Immune Mediators: Implications for Facioscapulohumeral Dystrophy.. Developmental cell. 22(1):38-51. Abstract
Young JM, Whiddon JL, Yao Z, Kasinathan B, Snider L, Geng LN, Balog J, Tawil R, van der Maarel SM, Tapscott SJ.  2013.  DUX4 binding to retroelements creates promoters that are active in FSHD muscle and testis.. PLoS genetics. 9(11):e1003947. Abstract
Thijssen PE, Balog J, Yao Z, Pham TP, Tawil R, Tapscott SJ, van der Maarel SM.  2014.  DUX4 promotes transcription of FRG2 by directly activating its promoter in facioscapulohumeral muscular dystrophy.. Skeletal muscle. 4:19. Abstract
Shadle SC, Zhong JW, Campbell AE, Conerly ML, Jagannathan S, Wong C-J, Morello TD, van der Maarel SM, Tapscott SJ.  2017.  DUX4-induced dsRNA and MYC mRNA stabilization activate apoptotic pathways in human cell models of facioscapulohumeral dystrophy.. PLoS genetics. 13(3):e1006658. Abstract