Center-Authored Papers

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Wang J, Wegener JE, Huang T-W, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J et al..  2015.  Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.. Nature. 521(7552):E1-4.
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Mahajan SS, Leko V, Simon JA, Bedalov A.  2011.  Sirtuin modulators.. Handbook of experimental pharmacology. (206):241-55. Abstract
Leko V, Varnum-Finney B, Li H, Gu Y, Flowers D, Nourigat C, Bernstein ID, Bedalov A.  2012.  SIRT1 is dispensable for function of hematopoietic stem cells in adult mice.. Blood. 119(8):1856-1860. Abstract
Sripathy S, Leko V, Adrianse RL, Loe T, Foss EJ, Dalrymple E, Lao U, Gatbonton-Schwager T, Carter KT, Payer B et al..  2017.  Screen for reactivation of MeCP2 on the inactive X chromosome identifies the BMP/TGF-β superfamily as a regulator of XIST expression.. Proceedings of the National Academy of Sciences of the United States of America. Abstract
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Leko V, Park GJ, Lao U, Simon JA, Bedalov A.  2013.  Enterocyte-Specific Inactivation of SIRT1 Reduces Tumor Load in the APC(+/min) Mouse Model.. PloS one. 8(6):e66283. Abstract
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Mahajan SS, Scian M, Sripathy S, Posakony J, Lao U, Loe TK, Leko V, Thalhofer A, Schuler AD, Bedalov A et al..  2014.  Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues as Sirtuin Inhibitors.. Journal of medicinal chemistry. 57(8):3283-94. Abstract
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Wang J, Wegener JE, Huang T-W, Sripathy S, De Jesus-Cortes H, Xu P, Tran S, Knobbe W, Leko V, Britt J et al..  2015.  Corrigendum: Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.. Nature. 525(7570):552.
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Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ et al..  2011.  Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.. Nature. 477(7365):482-5. Abstract