Center-Authored Papers

Filters: Author is Trobridge, Grant D  [Clear All Filters]
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 
V
Hocum JD, Battrell LR, Maynard R, Adair JE, Beard BC, Rawlings DJ, Kiem H-P, Miller DG, Trobridge GD.  2015.  VISA - Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing.. BMC bioinformatics. 16:212. Abstract
S
Trobridge GD, Beard BC, Wu RA, Ironside C, Malik P, Kiem H-P.  2012.  Stem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency.. PloS one. 7(9):e45173. Abstract
Enssle J, Trobridge GD, Keyser KA, Ironside C, Beard BC, Kiem H-P.  2010.  Stable marking and transgene expression without progression to monoclonality in canine long-term hematopoietic repopulating cells transduced with lentiviral vectors.. Human gene therapy. 21(4):397-403. Abstract
Adair JE, Waters T, Haworth KG, Kubek SP, Trobridge GD, Hocum JD, Heimfeld S, Kiem H-P.  2016.  Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy.. Nature communications. 7:13173. Abstract
R
Kiem H-P, Ironside C, Beard BC, Trobridge GD.  2010.  A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells.. Experimental hematology. 38(9):819-22,822.e1-3. Abstract
P
Trobridge GD, Wu RA, Beard BC, Chiu SY, Muñoz NM, von Laer D, Rossi JJ, Kiem H-P.  2009.  Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection.. PloS one. 4(11):e7693. Abstract
Younan PM, Polacino P, Kowalski JP, Peterson CW, Maurice NJ, Williams NP, Ho O, Trobridge GD, von Laer D, Prlic M et al..  2013.  Positive selection of mC46-expressing CD4+ T cells and maintenance of virus specific immunity in a primate AIDS model.. Blood. Abstract
N
Rae DT, Hocum JD, Bii V, Deeg HJ, Trobridge GD.  2015.  A novel retroviral mutagenesis screen identifies prognostic genes in RUNX1 mediated myeloid leukemogenesis.. Oncotarget. 6(31):30664-30674. Abstract
Muñoz NM, Beard BC, Ryu BY, Luche RM, Trobridge GD, Rawlings DJ, Scharenberg AM, Kiem H-P.  2012.  Novel reporter systems for facile evaluation of I-SceI-mediated genome editing.. Nucleic acids research. 40(2) Abstract
Watts KL, Beard BC, Wood BL, Trobridge GD, Humphries KR, Adams AB, Nelson V, Kiem H-P.  2014.  No Evidence of Clonal Dominance after Transplant of HOXB4-Expanded Cord Blood Cells in a Nonhuman Primate Model.. Experimental hematology. Abstract
L
Beard BC, Sud R, Keyser KA, Ironside C, Neff T, Gerull S, Trobridge GD, Kiem H-P.  2009.  Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients.. Blood. 113(21):5094-103. Abstract
Trobridge GD, Horn PA, Beard BC, Kiem H-P.  2012.  Large animal models for foamy virus vector gene therapy.. Viruses. 4(12):3572-88. Abstract
I
Burtner CR, Beard BC, Kennedy DR, Wohlfahrt ME, Adair JE, Trobridge GD, Scharenberg AM, Torgerson TR, Rawlings DJ, Felsburg PJ et al..  2014.  Intravenous injection of a foamy virus vector to correct canine SCID-X1.. Blood. 123(23):3578-84. Abstract
H
Beard BC, Adair JE, Trobridge GD, Kiem H-P.  2014.  High-throughput genomic mapping of vector integration sites in gene therapy studies.. Methods in molecular biology (Clifton, N.J.). 1185:321-44. Abstract
Zhang X-B, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries KR, Kiem H-P.  2008.  High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.. The Journal of clinical investigation. 118(4):1502-10. Abstract
Watts KL, Nelson V, Wood BL, Trobridge GD, Beard BC, Humphries KR, Kiem H-P.  2012.  Hematopoietic stem cell expansion facilitates multilineage engraftment in a nonhuman primate cord blood transplantation model.. Experimental hematology. 40(3):187-196. Abstract
F
Trobridge GD, Allen J, Peterson L, Ironside C, Russell DW, Kiem H-P.  2009.  Foamy and lentiviral vectors transduce canine long-term repopulating cells at similar efficiency.. Human gene therapy. 20(5):519-23. Abstract
E
Adair JE, Beard BC, Trobridge GD, Neff T, Rockhill JK, Silbergeld DL, Mrugala MM, Kiem H-P.  2012.  Extended Survival of Glioblastoma Patients After Chemoprotective HSC Gene Therapy.. Science translational medicine. 4(133):133ra57. Abstract
Muñoz NM, Trobridge GD, Kiem H-P.  2009.  Ex vivo expansion and lentiviral transduction of Macaca nemestrina CD4+ T cells.. Journal of medical primatology. 38(6):438-43. Abstract
Trobridge GD, Beard BC, Gooch C, Wohlfahrt M, Olsen P, Fletcher J, Malik P, Kiem H-P.  2008.  Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors.. Blood. 111(12):5537-43. Abstract
Zhong B, Trobridge GD, Zhang X, Watts KL, Ramakrishnan A, Wohlfahrt M, Adair JE, Kiem H-P.  2011.  Efficient generation of nonhuman primate induced pluripotent stem cells.. Stem cells and development. 20(5):795-807. Abstract
Beard BC, Trobridge GD, Ironside C, McCune JS, Adair JE, Kiem H-P.  2010.  Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates.. The Journal of clinical investigation. 120(7):2345-54. Abstract
D
Watts K, Zhang X, Beard B, Chiu SY, Trobridge GD, Humphries KR, Kiem H-P.  2011.  Differential Effects of HOXB4 and NUP98-HOXA10hd on Hematopoietic Repopulating Cells in a Nonhuman Primate Model.. Human gene therapy. 22(12):1475-1482. Abstract
Humbert O, Gisch DW, Wohlfahrt ME, Adams AB, Greenberg PD, Schmitt TM, Trobridge GD, Kiem H-P.  2016.  Development of 3(rd) Generation Cocal Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T Cells.. Molecular therapy : the journal of the American Society of Gene Therapy. Abstract
C
Adair JE, Zhao X, Chien S, Fang M, Wohlfahrt ME, Trobridge GD, Taylor JA, Beard BC, Kiem H-P, Becker PS.  2012.  Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities.. Journal of molecular medicine (Berlin, Germany). 90(11):1283-1294. Abstract