Center-Authored Papers

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Zinc Fingers
Kiem H-P, Ironside C, Beard BC, Trobridge GD.  2010.  A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells.. Experimental hematology. 38(9):819-22,822.e1-3. Abstract
Whole-Body Irradiation
Trobridge GD, Allen J, Peterson L, Ironside C, Russell DW, Kiem H-P.  2009.  Foamy and lentiviral vectors transduce canine long-term repopulating cells at similar efficiency.. Human gene therapy. 20(5):519-23. Abstract
Virus Integration
Kiem H-P, Ironside C, Beard BC, Trobridge GD.  2010.  A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells.. Experimental hematology. 38(9):819-22,822.e1-3. Abstract
Viral Envelope Proteins
Trobridge GD, Wu RA, Hansen M, Ironside C, Watts KL, Olsen P, Beard BC, Kiem H-P.  2010.  Cocal-pseudotyped lentiviral vectors resist inactivation by human serum and efficiently transduce primate hematopoietic repopulating cells.. Molecular therapy : the journal of the American Society of Gene Therapy. 18(4):725-33. Abstract
Translational Bioimaging Center Core Facility
Zhang X-B, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries KR, Kiem H-P.  2008.  High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.. The Journal of clinical investigation. 118(4):1502-10. Abstract
Li X, Xu F, Karoopongse E, Marcondes AM, Lee K, Kowdley KV, Miao CH, Trobridge GD, Campbell JS, Deeg HJ.  2013.  Allogeneic Transplantations, Fas Signaling, and Dysregulation of Hepcidin.. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 19(8):1210-9. Abstract
Transgenes
Trobridge GD, Wu RA, Beard BC, Chiu SY, Muñoz NM, von Laer D, Rossi JJ, Kiem H-P.  2009.  Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection.. PloS one. 4(11):e7693. Abstract
Beard BC, Trobridge GD, Ironside C, McCune JS, Adair JE, Kiem H-P.  2010.  Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates.. The Journal of clinical investigation. 120(7):2345-54. Abstract
Trobridge GD, Beard BC, Gooch C, Wohlfahrt M, Olsen P, Fletcher J, Malik P, Kiem H-P.  2008.  Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors.. Blood. 111(12):5537-43. Abstract
Enssle J, Trobridge GD, Keyser KA, Ironside C, Beard BC, Kiem H-P.  2010.  Stable marking and transgene expression without progression to monoclonality in canine long-term hematopoietic repopulating cells transduced with lentiviral vectors.. Human gene therapy. 21(4):397-403. Abstract
Transfection
Zhong B, Trobridge GD, Zhang X, Watts KL, Ramakrishnan A, Wohlfahrt M, Adair JE, Kiem H-P.  2011.  Efficient generation of nonhuman primate induced pluripotent stem cells.. Stem cells and development. 20(5):795-807. Abstract
Transduction, Genetic
Kiem H-P, Ironside C, Beard BC, Trobridge GD.  2010.  A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells.. Experimental hematology. 38(9):819-22,822.e1-3. Abstract
Trobridge GD, Allen J, Peterson L, Ironside C, Russell DW, Kiem H-P.  2009.  Foamy and lentiviral vectors transduce canine long-term repopulating cells at similar efficiency.. Human gene therapy. 20(5):519-23. Abstract
Trobridge GD, Wu RA, Hansen M, Ironside C, Watts KL, Olsen P, Beard BC, Kiem H-P.  2010.  Cocal-pseudotyped lentiviral vectors resist inactivation by human serum and efficiently transduce primate hematopoietic repopulating cells.. Molecular therapy : the journal of the American Society of Gene Therapy. 18(4):725-33. Abstract
Trobridge GD, Beard BC, Gooch C, Wohlfahrt M, Olsen P, Fletcher J, Malik P, Kiem H-P.  2008.  Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors.. Blood. 111(12):5537-43. Abstract
Enssle J, Trobridge GD, Keyser KA, Ironside C, Beard BC, Kiem H-P.  2010.  Stable marking and transgene expression without progression to monoclonality in canine long-term hematopoietic repopulating cells transduced with lentiviral vectors.. Human gene therapy. 21(4):397-403. Abstract
TRANSCRIPTION FACTORS
Watts K, Zhang X, Beard B, Chiu SY, Trobridge GD, Humphries KR, Kiem H-P.  2011.  Differential Effects of HOXB4 and NUP98-HOXA10hd on Hematopoietic Repopulating Cells in a Nonhuman Primate Model.. Human gene therapy. 22(12):1475-1482. Abstract
Time Factors
Enssle J, Trobridge GD, Keyser KA, Ironside C, Beard BC, Kiem H-P.  2010.  Stable marking and transgene expression without progression to monoclonality in canine long-term hematopoietic repopulating cells transduced with lentiviral vectors.. Human gene therapy. 21(4):397-403. Abstract
Zhang X-B, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries KR, Kiem H-P.  2008.  High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.. The Journal of clinical investigation. 118(4):1502-10. Abstract
Stem Cells
Beard BC, Trobridge GD, Ironside C, McCune JS, Adair JE, Kiem H-P.  2010.  Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates.. The Journal of clinical investigation. 120(7):2345-54. Abstract
Stem Cell Transplantation
Zhang X-B, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries KR, Kiem H-P.  2008.  High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.. The Journal of clinical investigation. 118(4):1502-10. Abstract
Specimen Processing Core Facility
Rae DT, Hocum JD, Bii V, Deeg HJ, Trobridge GD.  2015.  A novel retroviral mutagenesis screen identifies prognostic genes in RUNX1 mediated myeloid leukemogenesis.. Oncotarget. 6(31):30664-30674. Abstract
Zhang X-B, Beard BC, Trobridge GD, Wood BL, Sale GE, Sud R, Humphries KR, Kiem H-P.  2008.  High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector.. The Journal of clinical investigation. 118(4):1502-10. Abstract
SOXB1 Transcription Factors
Zhong B, Trobridge GD, Zhang X, Watts KL, Ramakrishnan A, Wohlfahrt M, Adair JE, Kiem H-P.  2011.  Efficient generation of nonhuman primate induced pluripotent stem cells.. Stem cells and development. 20(5):795-807. Abstract
Simian immunodeficiency virus
Muñoz NM, Trobridge GD, Kiem H-P.  2009.  Ex vivo expansion and lentiviral transduction of Macaca nemestrina CD4+ T cells.. Journal of medical primatology. 38(6):438-43. Abstract