Center-Authored Papers

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Wang L-S, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JGD, Cannon-Albright L, Baldwin CT, Zetterberg H et al..  2015.  Rarity of the Alzheimer disease-protective APP A673T variant in the United States.. JAMA neurology. 72(2):209-16. Abstract
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Trinidad SB, Fullerton SM, Bares JM, Jarvik GP, Larson EB, Burke W.  2012.  Informed Consent in Genome-Scale Research: What Do Prospective Participants Think? AJOB primary research. 3(3):3-11. Abstract
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Smith NL, Harrington LB, Blondon M, Wiggins KL, Floyd JS, Sitlani CM, McKnight B, Larson EB, Rosendaal FR, Heckbert SR et al..  2016.  The Association of Statin Therapy with the Risk of Recurrent Venous Thrombosis.. Journal of thrombosis and haemostasis : JTH. Abstract
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC et al..  2017.  Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.. Nature genetics. Abstract
Schully SD, Carrick DM, Mechanic LE, Srivastava S, Anderson GL, Baron JA, Berg CD, Cullen J, Diamandis EP, Doria-Rose PV et al..  2015.  Leveraging biospecimen resources for discovery or validation of markers for early cancer detection.. Journal of the National Cancer Institute. 107(4) Abstract
Schmidt AF, Swerdlow DI, Holmes MV, Patel RS, Fairhurst-Hunter Z, Lyall DM, Hartwig FP, Horta BL, Hyppönen E, Power C et al..  2016.  PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.. The lancet. Diabetes & endocrinology. Abstract
Schick UM, McDavid A, Crane PK, Weston N, Ehrlich K, Newton KM, Wallace R, Bookman E, Harrison T, Aragaki A et al..  2013.  Confirmation of the reported association of clonal chromosomal mosaicism with an increased risk of incident hematologic cancer.. PloS one. 8(3):e59823. Abstract
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Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA et al..  2013.  Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk.. Circulation. 127(13):1377-85. Abstract
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Naj AC, Jun G, Beecham GW, Wang L-S, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK et al..  2011.  Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.. Nature genetics. 43(5):436-41. Abstract
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McDavid A, Crane PK, Newton KM, Crosslin DR, McCormick W, Weston N, Ehrlich K, Hart E, Harrison R, Kukull WA et al..  2013.  Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records.. PloS one. 8(6):e63481. Abstract
Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y, Schurmann C, Highland HM et al..  2017.  Rare and low-frequency coding variants alter human adult height.. Nature. 542(7640):186-190. Abstract
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Johnson KE, Tachibana C, Coronado GD, Dember LM, Glasgow RE, Huang SS, Martin PJ, Richards J, Rosenthal G, Septimus E et al..  2014.  A guide to research partnerships for pragmatic clinical trials.. BMJ (Clinical research ed.). 349:g6826.
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Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A et al..  2017.  Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.. BioData mining. 10:25. Abstract
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Gray SL, Anderson ML, Hubbard RA, Lacroix A, Crane PK, McCormick W, Bowen JD, McCurry SM, Larson EB.  2013.  Frailty and Incident Dementia.. The journals of gerontology. Series A, Biological sciences and medical sciences. Abstract
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De R, Verma SS, Holzinger E, Hall M, Burt A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ et al..  2016.  Identifying gene-gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts.. Human genetics. Abstract
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Crosslin DR, McDavid A, Weston N, Zheng X, Hart E, de Andrade M, Kullo IJ, McCarty CA, Doheny KF, Pugh E et al..  2013.  Genetic variation associated with circulating monocyte count in the eMERGE Network.. Human molecular genetics. 22(10):2119-2127. Abstract
Crosslin DR, McDavid A, Weston N, Nelson SC, Zheng X, Hart E, de Andrade M, Kullo IJ, McCarty CA, Doheny KF et al..  2012.  Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network.. Human genetics. 131(4):639-652. Abstract