Center-Authored Papers

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Journal Article
Holmes MV, Dale CE, Zuccolo L, Silverwood RJ, Guo Y, Ye Z, Prieto-Merino D, Dehghan A, Trompet S, Wong A et al..  2014.  Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.. BMJ (Clinical research ed.). 349:g4164. Abstract
Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M et al..  2014.  Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.. American journal of human genetics. 94(2):223-32. Abstract
van Meurs JBJ, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, Mälarstig A, Bandinelli S et al..  2013.  Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.. The American journal of clinical nutrition. Abstract
de Vries PS, Sabater-Lleal M, Chasman DI, Trompet S, Ahluwalia TS, Teumer A, Kleber ME, Chen M-H, Wang JJ, Attia JR et al..  2017.  Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.. PloS one. 12(1):e0167742. Abstract
Fehringer G, Kraft P, Pharoah PDP, Eeles RA, Chatterjee N, Schumacher FR, Schildkraut JM, Lindstrom S, Brennan P, Bickeböller H et al..  2016.  Cross-cancer genome-wide analysis of lung, ovary, breast, prostate and colorectal cancer reveals novel pleiotropic associations.. Cancer research. 76(17):5103-5114. Abstract
van der Laan SW, Fall T, Soumaré A, Teumer A, Sedaghat S, Baumert J, Zabaneh D, van Setten J, Isgum I, Galesloot TE et al..  2016.  Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study.. Journal of the American College of Cardiology. 68(9):934-45. Abstract
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J'an, Kutalik Z et al..  2014.  Defining the role of common variation in the genomic and biological architecture of adult human height.. Nature genetics. 46(11):1173-86. Abstract
Iotchkova V, Huang J, Morris JA, Jain D, Barbieri C, Walter K, Min JL, Chen L, Astle W, Cocca M et al..  2016.  Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps.. Nature genetics. Abstract
Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu C-J et al..  2016.  DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.. American journal of human genetics. 98(4):680-96. Abstract
Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai P-C, Roetker NS, Just AC, Demerath EW, Guan W et al..  2016.  DNA methylation-based measures of biological age: meta-analysis predicting time to death.. Aging. 8(9):1844-1865. Abstract
Chami N, Chen M-H, Slater AJ, Eicher JD, Evangelou E, Tajuddin SM, Love-Gregory L, Kacprowski T, Schick UM, Nomura A et al..  2016.  Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.. American journal of human genetics. Abstract
Christophersen IE, Magnani JW, Yin X, Barnard J, Weng L-C, Arking DE, Niemeijer MN, Lubitz SA, Avery CL, Duan Q et al..  2017.  Fifteen Genetic Loci Associated With the Electrocardiographic P Wave.. Circulation. Cardiovascular genetics. 10(4) Abstract
Joshi AD, Andersson C, Buch S, Stender S, Noordam R, Weng L-C, Weeke PE, Auer PL, Boehm B, Chen C et al..  2016.  Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-wide Association Studies.. Gastroenterology. 151(2):351-363. Abstract
Yang J, Loos RJF, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R et al..  2012.  FTO genotype is associated with phenotypic variability of body mass index.. Nature. 490(7419):267-72. Abstract
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y et al..  2016.  Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.. Nature communications. 7:10023. Abstract
Nolte IM, Munoz LM, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B et al..  2017.  Genetic loci associated with heart rate variability and their effects on cardiac disease risk.. Nature communications. 8:15805. Abstract
Sim X, Jensen RA, Ikram KM, Cotch MF, Li X, Macgregor S, Xie J, Smith AV, Boerwinkle E, Mitchell P et al..  2013.  Genetic loci for retinal arteriolar microcirculation.. PloS one. 8(6):e65804. Abstract
Traylor M, Farrall M, Holliday EG, Sudlow C, Hopewell JC, Cheng Y-C, Fornage M, Ikram AM, Malik R, Bevan S et al..  2012.  Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies.. Lancet neurology. 11(11):951-962. Abstract
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J et al..  2015.  Genetic studies of body mass index yield new insights for obesity biology.. Nature. 518(7538):197-206. Abstract
Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang S-J et al..  2011.  Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.. Nature. 478(7367):103-9. Abstract
Coviello AD, Haring R, Wellons M, Vaidya D, Lehtimäki T, Keildson S, Lunetta KL, He C, Fornage M, Lagou V et al..  2012.  A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation.. PLoS genetics. 8(7):e1002805. Abstract
Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin S-Y, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD et al..  2012.  Genome-wide association study for circulating levels of plasminogen activator inhibitor-1 (PAI-1) provides novel insights into the regulation of PAI-1.. Blood. Abstract
Huang J, Huffman JE, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët D-A, Chen W-M, Smith NL, Kleber ME et al..  2014.  Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2.. Arteriosclerosis, thrombosis, and vascular biology. Abstract
O'Donnell CJ, Kavousi M, Smith AV, Kardia SLR, Feitosa MF, Hwang S-J, Sun YV, Province MA, Aspelund T, Dehghan A et al..  2011.  Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction.. Circulation. 124(25):2855-2864. Abstract
Dehghan A, Bis JC, White CC, Smith AV, Morrison AC, Cupples AL, Trompet S, Chasman DI, Lumley T, Völker U et al..  2016.  Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium.. PloS one. 11(3):e0144997. Abstract