Center-Authored Papers

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Journal Article
Dunlop MG, Dobbins SE, Farrington SM, Jones AM, Palles C, Whiffin N, Tenesa A, Spain S, Broderick P, Ooi L-Y et al..  2012.  Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk.. Nature genetics. 44(7):770-6. Abstract
Dunlop MG, Tenesa A, Farrington SM, Ballereau S, Brewster DH, Koessler T, Pharoah P, Schafmayer C, Hampe J, Völzke H et al..  2012.  Cumulative impact of common genetic variants and other risk factors on colorectal cancer risk in 42 103 individuals.. Gut. Abstract
Whiffin N, Dobbins SE, Hosking FJ, Palles C, Tenesa A, Wang Y, Farrington SM, Jones AM, Broderick P, Campbell H et al..  2013.  Deciphering the genetic architecture of low-penetrance susceptibility to colorectal cancer.. Human molecular genetics. 22(24):5075-82. Abstract
Wood AR, Esko T, Yang J, Vedantam S, Pers TH, Gustafsson S, Chu AY, Estrada K, Luan J'an, Kutalik Z et al..  2014.  Defining the role of common variation in the genomic and biological architecture of adult human height.. Nature genetics. 46(11):1173-86. Abstract
Carvajal-Carmona LG, Cazier J-B, Jones AM, Howarth K, Broderick P, Pittman A, Dobbins S, Tenesa A, Farrington S, Prendergast J et al..  2011.  Fine-mapping of colorectal cancer susceptibility loci at 8q23.3, 16q22.1 and 19q13.11: refinement of association signals and use of in silico analysis to suggest functional variation and unexpected candidate target genes.. Human molecular genetics. 20(14):2879-88. Abstract
Yang J, Loos RJF, Powell JE, Medland SE, Speliotes EK, Chasman DI, Rose LM, Thorleifsson G, Steinthorsdottir V, Mägi R et al..  2012.  FTO genotype is associated with phenotypic variability of body mass index.. Nature. 490(7419):267-72. Abstract
Pattaro C, Teumer A, Gorski M, Chu AY, Li M, Mijatovic V, Garnaas M, Tin A, Sorice R, Li Y et al..  2016.  Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.. Nature communications. 7:10023. Abstract
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J et al..  2015.  Genetic studies of body mass index yield new insights for obesity biology.. Nature. 518(7538):197-206. Abstract
Ehret GB, Munroe PB, Rice KM, Bochud M, Johnson AD, Chasman DI, Smith AV, Tobin MD, Verwoert GC, Hwang S-J et al..  2011.  Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.. Nature. 478(7367):103-9. Abstract
Huang J, Huffman JE, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët D-A, Chen W-M, Smith NL, Kleber ME et al..  2014.  Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2.. Arteriosclerosis, thrombosis, and vascular biology. Abstract
Berndt SI, Gustafsson S, Mägi R, Ganna A, Wheeler E, Feitosa MF, Justice AE, Monda KL, Croteau-Chonka DC, Day FR et al..  2013.  Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.. Nature genetics. 45(5):501-12. Abstract
Justice AE, Winkler TW, Feitosa MF, Graff M, Fisher VA, Young K, Barata L, Deng X, Czajkowski J, Hadley D et al..  2017.  Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.. Nature communications. 8:14977. Abstract
Graff M, Scott RA, Justice AE, Young KL, Feitosa MF, Barata L, Winkler TW, Chu AY, Mahajan A, Hadley D et al..  2017.  Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.. PLoS genetics. 13(4):e1006528. Abstract
Whiffin N, Hosking F, Farrington SM, Palles C, Dobbins S, Zgaga L, Lloyd A, Kinnersley B, Gorman M, Tenesa A et al..  2014.  Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.. Human molecular genetics. Abstract
Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T, Fall T, Kilpeläinen TO et al..  2015.  The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.. PLoS genetics. 11(10):e1005378. Abstract
Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B et al..  2015.  Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.. Nature genetics. 47(11):1294-1303. Abstract
Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B et al..  2015.  Large-Scale Genomic Analyses Link Reproductive Aging to Hypothalamic Signaling, Breast Cancer Susceptibility, and BRCA1-Mediated DNA Repair--Editorial Comment. Obstetrical & Gynecological Survey. 70(12):758-762.
Jarvis D, Mitchell JS, Law PJ, Palin K, Tuupanen S, Gylfe A, Hänninen UA, Cajuso T, Tanskanen T, Kondelin J et al..  2016.  Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer.. British journal of cancer. Abstract
Rodriguez-Broadbent H, Law PJ, Sud A, Palin K, Tuupanen S, Gylfe A, Hänninen UA, Cajuso T, Tanskanen T, Kondelin J et al..  2017.  Mendelian randomisation implicates hyperlipidaemia as a risk factor for colorectal cancer.. International journal of cancer. Abstract
de Vries PS, Chasman DI, Sabater-Lleal M, Chen M-H, Huffman JE, Steri M, Tang W, Teumer A, Marioni RE, Grossmann V et al..  2016.  A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.. Human molecular genetics. 25(2):358-70. Abstract
Cheng TH, Thompson D, Painter J, O'Mara T, Gorman M, Martin L, Palles C, Jones A, Buchanan DD, Win AK et al..  2015.  Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.. Scientific reports. 5:17369. Abstract
Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S et al..  2013.  Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.. Circulation. 128(12):1310-24. Abstract
Tomlinson IPM, Carvajal-Carmona LG, Dobbins SE, Tenesa A, Jones AM, Howarth K, Palles C, Broderick P, Jaeger EEM, Farrington S et al..  2011.  Multiple common susceptibility variants near BMP pathway loci GREM1, BMP4, and BMP2 explain part of the missing heritability of colorectal cancer.. PLoS genetics. 7(6):e1002105. Abstract
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE et al..  2015.  New genetic loci link adipose and insulin biology to body fat distribution.. Nature. 518(7538):187-96. Abstract
Al-Tassan NA, Whiffin N, Hosking FJ, Palles C, Farrington SM, Dobbins SE, Harris R, Gorman M, Tenesa A, Meyer BF et al..  2015.  A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.. Scientific reports. 5:10442. Abstract