Center-Authored Papers

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Holzinger ER, Verma SS, Moore CB, Hall M, De R, Gilbert-Diamond D, Lanktree MB, Pankratz N, Amuzu A, Burt A et al..  2017.  Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals.. BioData mining. 10:25. Abstract
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Fesinmeyer MD, North KE, Lim U, Bůžková P, Crawford DC, Haessler J, Gross MD, Fowke JH, Goodloe R, Love S-A et al..  2013.  Effects of smoking on the genetic risk of obesity: the population architecture using genomics and epidemiology study.. BMC medical genetics. 14:6. Abstract
McDavid A, Crane PK, Newton KM, Crosslin DR, McCormick W, Weston N, Ehrlich K, Hart E, Harrison R, Kukull WA et al..  2013.  Enhancing the power of genetic association studies through the use of silver standard cases derived from electronic medical records.. PloS one. 8(6):e63481. Abstract
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Gong J, Schumacher F, Lim U, Hindorff LA, Haessler J, Buyske S, Carlson CS, Rosse S, Bůžková P, Fornage M et al..  2013.  Fine Mapping and Identification of BMI Loci in African Americans.. American journal of human genetics. 93(4):661-71. Abstract
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Carlson CS, Matise TC, North KE, Haiman CA, Fesinmeyer MD, Buyske S, Schumacher FR, Peters U, Franceschini N, Ritchie MD et al..  2013.  Generalization and dilution of association results from European GWAS in populations of non-European ancestry: the PAGE study.. PLoS biology. 11(9):e1001661. Abstract
Fesinmeyer MD, North KE, Ritchie MD, Lim U, Franceschini N, Wilkens LR, Gross MD, Bůžková P, Glenn K, Quibrera MP et al..  2012.  Genetic Risk Factors for BMI and Obesity in an Ethnically Diverse Population: Results From the Population Architecture Using Genomics and Epidemiology (PAGE) Study.. Obesity (Silver Spring, Md.). Abstract
Fesinmeyer MD, North KE, Ritchie MD, Lim U, Franceschini N, Wilkens LR, Gross MD, Bůžková P, Glenn K, Quibrera MP et al..  2013.  Genetic risk factors for BMI and obesity in an ethnically diverse population: Results from the population architecture using genomics and epidemiology (PAGE) study.. Obesity (Silver Spring, Md.). 21(4):835-46. Abstract
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J et al..  2015.  Genetic studies of body mass index yield new insights for obesity biology.. Nature. 518(7538):197-206. Abstract
Crosslin DR, McDavid A, Weston N, Nelson SC, Zheng X, Hart E, de Andrade M, Kullo IJ, McCarty CA, Doheny KF et al..  2012.  Genetic variants associated with the white blood cell count in 13,923 subjects in the eMERGE Network.. Human genetics. 131(4):639-652. Abstract
Spencer KL, Malinowski J, Carty CL, Franceschini N, Fernández-Rhodes L, Young A, Cheng I, Ritchie MD, Haiman CA, Wilkens L et al..  2013.  Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study.. PloS one. 8(2):e55258. Abstract
Crosslin DR, McDavid A, Weston N, Zheng X, Hart E, de Andrade M, Kullo IJ, McCarty CA, Doheny KF, Pugh E et al..  2013.  Genetic variation associated with circulating monocyte count in the eMERGE Network.. Human molecular genetics. 22(10):2119-2127. Abstract
Ritchie MD, Denny JC, Zuvich RL, Crawford DC, Schildcrout JS, Bastarache L, Ramirez AH, Mosley JD, Pulley JM, Basford MA et al..  2013.  Genome- and phenome-wide analyses of cardiac conduction identifies markers of arrhythmia risk.. Circulation. 127(13):1377-85. Abstract
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Rasmussen-Torvik LJ, Pacheco JA, Wilke RA, Thompson WK, Ritchie MD, Kho AN, Muthalagu A, Hayes GM, Armstrong LL, Scheftner DA et al..  2012.  High density GWAS for LDL cholesterol in African Americans using electronic medical records reveals a strong protective variant in APOE.. Clinical and translational science. 5(5):394-9. Abstract
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De R, Verma SS, Holzinger E, Hall M, Burt A, Carrell DS, Crosslin DR, Jarvik GP, Kuivaniemi H, Kullo IJ et al..  2016.  Identifying gene-gene interactions that are highly associated with four quantitative lipid traits across multiple cohorts.. Human genetics. Abstract
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Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE et al..  2015.  New genetic loci link adipose and insulin biology to body fat distribution.. Nature. 518(7538):187-96. Abstract
Matise TC, Ambite JL, Buyske S, Carlson CS, Cole SA, Crawford DC, Haiman CA, Heiss G, Kooperberg C, Le Marchand L et al..  2011.  The Next PAGE in Understanding Complex Traits: Design for the Analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study.. American journal of epidemiology. 174(7):849-59. Abstract
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Schmidt AF, Swerdlow DI, Holmes MV, Patel RS, Fairhurst-Hunter Z, Lyall DM, Hartwig FP, Horta BL, Hyppönen E, Power C et al..  2016.  PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.. The lancet. Diabetes & endocrinology. Abstract
Pendergrass SA, Brown-Gentry K, Dudek S, Frase A, Torstenson ES, Goodloe R, Ambite JL, Avery CL, Buyske S, Bůžková P et al..  2013.  Phenome-Wide Association Study (PheWAS) for Detection of Pleiotropy within the Population Architecture using Genomics and Epidemiology (PAGE) Network.. PLoS genetics. 9(1):e1003087. Abstract
Avery CL, He Q, North KE, Ambite JL, Boerwinkle E, Fornage M, Hindorff LA, Kooperberg C, Meigs JB, Pankow JS et al..  2011.  A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains.. PLoS genetics. 7(10):e1002322. Abstract
Zuvich RL, Armstrong LL, Bielinski SJ, Bradford Y, Carlson CS, Crawford DC, Crenshaw AT, de Andrade M, Doheny KF, Haines JL et al..  2011.  Pitfalls of merging GWAS data: lessons learned in the eMERGE network and quality control procedures to maintain high data quality.. Genetic epidemiology. 35(8):887-98. Abstract
Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpeläinen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD et al..  2014.  Pleiotropic genes for metabolic syndrome and inflammation.. Molecular genetics and metabolism. Abstract
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Turner S, Armstrong LL, Bradford Y, Carlson CS, Crawford DC, Crenshaw AT, de Andrade M, Doheny KF, Haines JL, Hayes G et al..  2011.  Quality control procedures for genome-wide association studies.. Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.]. Chapter 1:Unit1.19. Abstract
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Fullerton SM, Wolf WA, Brothers KB, Clayton EW, Crawford DC, Denny JC, Greenland P, Koenig BA, Leppig KA, Lindor NM et al..  2012.  Return of individual research results from genome-wide association studies: experience of the Electronic Medical Records and Genomics (eMERGE) Network.. Genetics in medicine : official journal of the American College of Medical Genetics. Abstract
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Fernández-Rhodes L, Gong J, Haessler J, Franceschini N, Graff M, Nishimura KK, Wang Y, Highland HM, Yoneyama S, Bush WS et al..  2017.  Trans-ethnic fine-mapping of genetic loci for body mass index in the diverse ancestral populations of the Population Architecture using Genomics and Epidemiology (PAGE) Study reveals evidence for multiple signals at established loci.. Human genetics. Abstract