Center-Authored Papers

Filters: Author is Grady, William M  [Clear All Filters]
2008
Rojas A, Meherem S, Kim Y-H, Washington MK, Willis JE, Markowitz SD, Grady WM.  2008.  The aberrant methylation of TSP1 suppresses TGF-beta1 activation in colorectal cancer.. International journal of cancer. Journal international du cancer. 123(1):14-21. Abstract
Lynch HT, Kaurah P, Wirtzfeld D, Rubinstein WS, Weissman S, Lynch JF, Grady WM, Wiyrick S, Senz J, Huntsman DG.  2008.  Hereditary diffuse gastric cancer: diagnosis, genetic counseling, and prophylactic total gastrectomy.. Cancer. 112(12):2655-63. Abstract
Grady WM, Parkin RK, Mitchell PS, Lee JH, Kim Y-H, Tsuchiya KD, Washington MK, Paraskeva C, Willson JKV, Kaz AM et al..  2008.  Epigenetic silencing of the intronic microRNA hsa-miR-342 and its host gene EVL in colorectal cancer.. Oncogene. 27(27):3880-8. Abstract
Grady WM, Carethers JM.  2008.  Genomic and epigenetic instability in colorectal cancer pathogenesis.. Gastroenterology. 135(4):1079-99. Abstract
Muñoz NM, Baek JY, Grady WM.  2008.  TGF-beta has paradoxical and context dependent effects on proliferation and anoikis in human colorectal cancer cell lines.. Growth factors (Chur, Switzerland). 26(5):254-62. Abstract
2009
Chak A, Falk G, Grady WM, Kinnard M, Elston R, Mittal S, King JF, Willis JE, Kondru A, Brock W et al..  2009.  Assessment of familiality, obesity, and other risk factors for early age of cancer diagnosis in adenocarcinomas of the esophagus and gastroesophageal junction.. The American journal of gastroenterology. 104(8):1913-21. Abstract
Ausch C, Kim Y-H, Tsuchiya KD, Dzieciatkowski S, Washington MK, Paraskeva C, Radich JP, Grady WM.  2009.  Comparative analysis of PCR-based biomarker assay methods for colorectal polyp detection from fecal DNA.. Clinical chemistry. 55(8):1559-63. Abstract
Rojas A, Padidam M, Cress D, Grady WM.  2009.  TGF-beta receptor levels regulate the specificity of signaling pathway activation and biological effects of TGF-beta.. Biochimica et biophysica acta. 1793(7):1165-73. Abstract
Trobridge P, Knoblaugh SE, Washington KM, Munoz NM, Tsuchiya KD, Rojas A, Song X, Ulrich CM, Sasazuki T, Shirasawa S et al..  2009.  TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway.. Gastroenterology. 136(5):1680-8.e7. Abstract
2010
Holmes RS, Zheng Y, Baron JA, Li L, McKeown-Eyssen G, Newcomb PA, Stern MC, Haile RW, Grady WM, Potter JD et al..  2010.  Use of folic acid-containing supplements after a diagnosis of colorectal cancer in the Colon Cancer Family Registry.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 19(8):2023-34. Abstract
Ulrich CM, Grady WM.  2010.  Linking epidemiology to epigenomics--where are we today? Cancer prevention research (Philadelphia, Pa.). 3(12):1505-8. Abstract
Borinstein SC, Conerly M, Dzieciatkowski S, Biswas S, Washington KM, Trobridge P, Henikoff S, Grady WM.  2010.  Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer model.. Molecular carcinogenesis. 49(1):94-103. Abstract
Grady WM, Tewari M.  2010.  The next thing in prognostic molecular markers: microRNA signatures of cancer.. Gut. 59(6):706-8.
Sun X, Elston R, Barnholtz-Sloan J, Falk G, Grady WM, Kinnard M, Mittal SK, Willis JE, Markowitz S, Brock W et al..  2010.  A segregation analysis of Barrett's esophagus and associated adenocarcinomas.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 19(3):666-74. Abstract
Conerly M, Grady WM.  2010.  Insights into the role of DNA methylation in disease through the use of mouse models.. Disease models & mechanisms. 3(5-6):290-7. Abstract
Baek JY, Morris SM, Campbell J, Fausto N, Yeh MM, Grady WM.  2010.  TGF-beta inactivation and TGF-alpha overexpression cooperate in an in vivo mouse model to induce hepatocellular carcinoma that recapitulates molecular features of human liver cancer.. International journal of cancer. Journal international du cancer. 127(5):1060-71. Abstract
2011
Kim Y-H, Lee HC, Kim S-Y, Yeom YI, Ryu KJ, Min B-H, Kim D-H, Son HJ, Rhee P-L, Kim JJ et al..  2011.  Epigenomic analysis of aberrantly methylated genes in colorectal cancer identifies genes commonly affected by epigenetic alterations.. Annals of surgical oncology. 18(8):2338-47. Abstract
Lao VV, Grady WM.  2011.  Epigenetics and colorectal cancer.. Nature reviews. Gastroenterology & hepatology. 8(12):686-700. Abstract
Kaz AM, Wong C-J, Luo Y, Virgin JB, Washington KM, Willis JE, Leidner RS, Chak A, Grady WM.  2011.  DNA methylation profiling in Barrett's esophagus and esophageal adenocarcinoma reveals unique methylation signatures and molecular subclasses.. Epigenetics : official journal of the DNA Methylation Society. 6(12):1403-12. Abstract
Pritchard CC, Grady WM.  2011.  Colorectal cancer molecular biology moves into clinical practice.. Gut. 60(1):116-29. Abstract
Cicek MS, Lindor NM, Gallinger S, Bapat B, Hopper JL, Jenkins MA, Young J, Buchanan D, Walsh MD, Le Marchand L et al..  2011.  Quality assessment and correlation of microsatellite instability and immunohistochemical markers among population- and clinic-based colorectal tumors results from the Colon Cancer Family Registry.. The Journal of molecular diagnostics : JMD. 13(3):271-81. Abstract
2012
Greer KB, Thompson CL, Brenner L, Bednarchik B, Dawson D, Willis J, Grady WM, Falk GW, Cooper GS, Li L et al..  2012.  Association of insulin and insulin-like growth factors with Barrett's oesophagus.. Gut. 61(5):665-672. Abstract
Patel N, Black J, Chen X, Marcondes AM, Grady WM, Lawlor ER, Borinstein SC.  2012.  DNA methylation and gene expression profiling of ewing sarcoma primary tumors reveal genes that are potential targets of epigenetic inactivation.. Sarcoma. 2012:498472. Abstract
Hernandez JM, Siegel EM, Riggs B, Eschrich S, Elahi A, Qu X, Ajidahun A, Berglund A, Coppola D, Grady WM et al..  2012.  DNA methylation profiling across the spectrum of HPV-associated anal squamous neoplasia.. PloS one. 7(11):e50533. Abstract
Kaz AM, Luo Y, Dzieciatkowski S, Chak A, Willis JE, Upton MP, Leidner RS, Grady WM.  2012.  Aberrantly methylated PKP1 in the progression of Barrett's esophagus to esophageal adenocarcinoma.. Genes, chromosomes & cancer. 51(4):393. Abstract