Center-Authored Papers

Filters: Author is Grim, Jonathan E  [Clear All Filters]
2018
Davis RJ, Gönen M, Margineantu DH, Handeli S, Swanger J, Hoellerbauer P, Paddison PJ, Gu H, Raftery D, Grim JE et al..  2018.  Pan-cancer transcriptional signatures predictive of oncogenic mutations reveal that Fbw7 regulates cancer cell oxidative metabolism.. Proceedings of the National Academy of Sciences of the United States of America. 115(21):5462-5467. Abstract
2015
Woo J, Cohen SA, Grim JE.  2015.  Targeted therapy in gastroesophageal cancers: past, present and future.. Gastroenterology report. Abstract
Cho E, Grim JE.  2015.  A (heat) shocking development: FBXW7 loss unleashes HSF1 to drive melanoma invasion and metastasis.. Pigment cell & melanoma research. Abstract
2014
Grim JE.  2014.  Fbxw7 hotspot mutations and human colon cancer: mechanistic insights from new mouse models.. Gut. 63(5):707-9.
2013
Welcker M, Larimore EA, Swanger J, Bengoechea-Alonso MT, Grim JE, Ericsson J, Zheng N, Clurman BE.  2013.  Fbw7 dimerization determines the specificity and robustness of substrate degradation.. Genes & development. 27(23):2531-6. Abstract
2012
Grim JE, Knoblaugh SE, Guthrie KA, Hagar A, Swanger J, Hespelt J, Delrow JJ, Small T, Grady WM, Nakayama KI et al..  2012.  Fbw7 and p53 Cooperatively Suppress Advanced and Chromosomally Unstable Intestinal Cancer.. Molecular and cellular biology. 32(11):2160-7. Abstract
2008
Grim JE, Gustafson MP, Hirata RK, Hagar AC, Swanger J, Welcker M, Hwang HC, Ericsson J, Russell DW, Clurman BE.  2008.  Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase.. The Journal of cell biology. 181(6):913-20. Abstract