Center-Authored Papers

Filters: Author is O'Donnell, Christopher J  [Clear All Filters]
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Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A, Schnabel RB, Lubos E, Keller T, Eleftheriadis MS et al..  2011.  A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease.. Circulation. Cardiovascular genetics. 4(4):403-12. Abstract
Weng L-C, Tang W, Rich SS, Smith NL, Redline S, O'Donnell CJ, Basu S, Reiner AP, Delaney JA, Tracy RP et al..  2014.  A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups.. Thrombosis research. Abstract
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de Vries PS, Chasman DI, Sabater-Lleal M, Chen M-H, Huffman JE, Steri M, Tang W, Teumer A, Marioni RE, Grossmann V et al..  2016.  A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration.. Human molecular genetics. 25(2):358-70. Abstract
de Vries PS, Sabater-Lleal M, Chasman DI, Trompet S, Ahluwalia TS, Teumer A, Kleber ME, Chen M-H, Wang JJ, Attia JR et al..  2017.  Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study.. PloS one. 12(1):e0167742. Abstract
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Crosby J, Peloso GM, Auer PL, Crosslin DR, Stitziel NO, Lange LA, Lu Y, Tang Z-Z, Zhang H, Hindy G et al..  2014.  Loss-of-function mutations in APOC3, triglycerides, and coronary disease.. The New England journal of medicine. 371(1):22-31. Abstract
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Tabor HK, Auer PL, Jamal SM, Chong JX, Yu J-H, Gordon AS, Graubert TA, O'Donnell CJ, Rich SS, Nickerson DA et al..  2014.  Pathogenic variants for mendelian and complex traits in exomes of 6,517 European and african americans: implications for the return of incidental results.. American journal of human genetics. 95(2):183-93. Abstract
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Soranzo N, Spector TD, Mangino M, Kühnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M et al..  2009.  A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium.. Nature genetics. 41(11):1182-90. Abstract
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC et al..  2017.  Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.. Nature genetics. Abstract
Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S et al..  2013.  Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.. Circulation. 128(12):1310-24. Abstract
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van Rooij FJA, Qayyum R, Smith AV, Zhou Y, Trompet S, Tanaka T, Keller MF, Chang L-C, Schmidt H, Yang M-L et al..  2016.  Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis.. American journal of human genetics. Abstract
Reiner AP, Lettre G, Nalls MA, Ganesh SK, Mathias R, Austin MA, Dean E, Arepalli S, Britton A, Chen Z et al..  2011.  Genome-wide association study of white blood cell count in 16,388 African Americans: the continental origins and genetic epidemiology network (COGENT).. PLoS genetics. 7(6):e1002108. Abstract
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Polfus LM, Khajuria RK, Schick UM, Pankratz N, Pazoki R, Brody JA, Chen M-H, Auer PL, Floyd JS, Huang J et al..  2016.  Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis.. American journal of human genetics. 99(2):481-8. Abstract
Peloso GM, Auer PL, Bis JC, Voorman A, Morrison AC, Stitziel NO, Brody JA, Khetarpal SA, Crosby JR, Fornage M et al..  2014.  Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks.. American journal of human genetics. 94(2):223-32. Abstract
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O'Donnell CJ, Kavousi M, Smith AV, Kardia SLR, Feitosa MF, Hwang S-J, Sun YV, Province MA, Aspelund T, Dehghan A et al..  2011.  Genome-Wide Association Study for Coronary Artery Calcification With Follow-Up in Myocardial Infarction.. Circulation. 124(25):2855-2864. Abstract
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Stitziel NO, Won H-H, Morrison AC, Peloso GM, Do R, Lange LA, Fontanillas P, Gupta N, Duga S, Goel A et al..  2014.  Inactivating mutations in NPC1L1 and protection from coronary heart disease.. The New England journal of medicine. 371(22):2072-82. Abstract
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van Meurs JBJ, Pare G, Schwartz SM, Hazra A, Tanaka T, Vermeulen SH, Cotlarciuc I, Yuan X, Mälarstig A, Bandinelli S et al..  2013.  Common genetic loci influencing plasma homocysteine concentrations and their effect on risk of coronary artery disease.. The American journal of clinical nutrition. Abstract
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Lucas G, Lluís-Ganella C, Subirana I, Musameh MD, Gonzalez JR, Nelson CP, Sentí M, Schwartz SM, Siscovick D, O'Donnell CJ et al..  2012.  Hypothesis-Based Analysis of Gene-Gene Interactions and Risk of Myocardial Infarction.. PloS one. 7(8):e41730. Abstract
Logsdon BA, Dai JY, Auer PL, Johnsen JM, Ganesh SK, Smith NL, Wilson JG, Tracy RP, Lange LA, Jiao S et al..  2014.  A variational Bayes discrete mixture test for rare variant association.. Genetic epidemiology. 38(1):21-30. Abstract
Liu C, Kraja AT, Smith JA, Brody JA, Franceschini N, Bis JC, Rice K, Morrison AC, Lu Y, Weiss S et al..  2016.  Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.. Nature genetics. 48(10):1162-1170. Abstract
Lin H, Wang M, Brody JA, Bis JC, Dupuis J, Lumley T, McKnight B, Rice KM, Sitlani CM, Reid JG et al..  2014.  Strategies to Design and Analyze Targeted Sequencing Data: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study.. Circulation. Cardiovascular genetics. 7(3):335-43. Abstract
Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang Z-Z, Bizon C, Lange EM, Smith JD, Turner EH et al..  2014.  Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol.. American journal of human genetics. 94(2):233-45. Abstract
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Kraja AT, Chasman DI, North KE, Reiner AP, Yanek LR, Kilpeläinen TO, Smith JA, Dehghan A, Dupuis J, Johnson AD et al..  2014.  Pleiotropic genes for metabolic syndrome and inflammation.. Molecular genetics and metabolism. Abstract
Keller MF, Reiner AP, Okada Y, van Rooij FJA, Johnson AD, Chen M-H, Smith AV, Morris AP, Tanaka T, Ferrucci L et al..  2014.  Trans-ethnic Meta-analysis of White Blood Cell Phenotypes.. Human molecular genetics. 23(25):6944-60. Abstract
Kathiresan S, Voight BF, Purcell S, Musunuru K, Ardissino D, Mannucci PM, Anand S, Engert JC, Samani NJ, Schunkert H et al..  2009.  Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.. Nature genetics. 41(3):334-41. Abstract
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Johansen CT, Wang J, Lanktree MB, McIntyre AD, Ban MR, Martins RA, Kennedy BA, Hassell RG, Visser ME, Schwartz SM et al..  2011.  An increased burden of common and rare lipid-associated risk alleles contributes to the phenotypic spectrum of hypertriglyceridemia.. Arteriosclerosis, thrombosis, and vascular biology. 31(8):1916-26. Abstract