Center-Authored Papers

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Weng L-C, Tang W, Rich SS, Smith NL, Redline S, O'Donnell CJ, Basu S, Reiner AP, Delaney JA, Tracy RP et al..  2014.  A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups.. Thrombosis research. Abstract
Walston JD, Matteini AM, Nievergelt C, Lange LA, Fallin DM, Barzilai N, Ziv E, Pawlikowska L, Kwok P, Cummings SR et al..  2009.  Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults.. Experimental gerontology. 44(5):350-5. Abstract
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Crosby J, Peloso GM, Auer PL, Crosslin DR, Stitziel NO, Lange LA, Lu Y, Tang Z-Z, Zhang H, Hindy G et al..  2014.  Loss-of-function mutations in APOC3, triglycerides, and coronary disease.. The New England journal of medicine. 371(1):22-31. Abstract
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Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S et al..  2013.  Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.. Circulation. 128(12):1310-24. Abstract
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Rivara MB, Zelnick LR, Hoofnagle AN, Newitt R, Tracy RP, Kratz M, Weigle DS, Kestenbaum BR.  2017.  Diurnal and Long-term Variation in Plasma Concentrations and Renal Clearances of Circulating Markers of Kidney Proximal Tubular Secretion.. Clinical chemistry. Abstract
Reiner AP, Carlson CS, Jenny NS, Durda PJ, Siscovick DS, Nickerson DA, Tracy RP.  2007.  USF1 gene variants, cardiovascular risk, and mortality in European Americans: analysis of two US cohort studies.. Arteriosclerosis, thrombosis, and vascular biology. 27(12):2736-42. Abstract
Reiner AP, Gross MD, Carlson CS, Bielinski SJ, Lange LA, Fornage M, Jenny NS, Walston J, Tracy RP, Williams DO et al..  2009.  Common coding variants of the HNF1A gene are associated with multiple cardiovascular risk phenotypes in community-based samples of younger and older European-American adults: the Coronary Artery Risk Development in Young Adults Study and The Cardiovascula. Circulation. Cardiovascular genetics. 2(3):244-54. Abstract
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Logsdon BA, Dai JY, Auer PL, Johnsen JM, Ganesh SK, Smith NL, Wilson JG, Tracy RP, Lange LA, Jiao S et al..  2014.  A variational Bayes discrete mixture test for rare variant association.. Genetic epidemiology. 38(1):21-30. Abstract
Lange LA, Carlson CS, Hindorff LA, Lange EM, Walston J, Durda PJ, Cushman M, Bis JC, Zeng D, Lin DY et al..  2006.  Association of polymorphisms in the CRP gene with circulating C-reactive protein levels and cardiovascular events.. JAMA : the journal of the American Medical Association. 296(22):2703-11. Abstract
Lange LA, Hu Y, Zhang H, Xue C, Schmidt EM, Tang Z-Z, Bizon C, Lange EM, Smith JD, Turner EH et al..  2014.  Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol.. American journal of human genetics. 94(2):233-45. Abstract
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Kuller LH, Bracken MB, Ogino S, Prentice RL, Tracy RP.  2013.  The Role of Epidemiology in the Era of Molecular Epidemiology and Genomics: Summary of the 2013 AJE-sponsored Society of Epidemiologic Research Symposium.. American journal of epidemiology. 178(9):1350-4. Abstract
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Hunt PW, Martin JN, Sinclair E, Epling L, Teague J, Jacobson MA, Tracy RP, Corey L, Deeks SG.  2011.  Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy.. The Journal of infectious diseases. 203(10):1474-83. Abstract
Huang J, Sabater-Lleal M, Asselbergs FW, Tregouet D, Shin S-Y, Ding J, Baumert J, Oudot-Mellakh T, Folkersen L, Johnson AD et al..  2012.  Genome-wide association study for circulating levels of plasminogen activator inhibitor-1 (PAI-1) provides novel insights into the regulation of PAI-1.. Blood. Abstract
Huang J, Huffman JE, Yamkauchi M, Trompet S, Asselbergs FW, Sabater-Lleal M, Trégouët D-A, Chen W-M, Smith NL, Kleber ME et al..  2014.  Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2.. Arteriosclerosis, thrombosis, and vascular biology. Abstract
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Glazer NL, Macy EM, Lumley T, Smith NL, Reiner AP, Psaty BM, King GL, Tracy RP, Siscovick DS.  2012.  Transforming growth factor beta-1 and incidence of heart failure in older adults: The Cardiovascular Health Study.. Cytokine. Abstract
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Ellis J, Lange EM, Li J, Dupuis J, Baumert J, Walston JD, Keating BJ, Durda P, Fox ER, Palmer CD et al..  2014.  Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans.. Human genetics. Abstract
Eicher JD, Chami N, Kacprowski T, Nomura A, Chen M-H, Yanek LR, Tajuddin SM, Schick UM, Slater AJ, Pankratz N et al..  2016.  Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals.. American journal of human genetics. Abstract
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Durda P, Sabourin J, Lange EM, Nalls MA, Mychaleckyj JC, Swords Jenny N, Li J, Walston J, Harris TB, Psaty BM et al..  2015.  Plasma Levels of Soluble IL-2 Receptor α: Associations With Clinical Cardiovascular Events and Genome-Wide Association Scan.. Arteriosclerosis, thrombosis, and vascular biology. Abstract
Do R, Stitziel NO, Won H-H, Jørgensen AB, Duga S, Merlini PA, Kiezun A, Farrall M, Goel A, Zuk O et al..  2015.  Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction.. Nature. 518(7537):102-6. Abstract
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Chami N, Chen M-H, Slater AJ, Eicher JD, Evangelou E, Tajuddin SM, Love-Gregory L, Kacprowski T, Schick UM, Nomura A et al..  2016.  Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits.. American journal of human genetics. Abstract
Carty CL, Cushman M, Jones D, Lange LA, Hindorff LA, Rice K, Jenny NS, Durda PJ, Walston J, Carlson CS et al..  2008.  Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults. The Cardiovascular Health Study.. Thrombosis and haemostasis. 99(2):388-95. Abstract
Carlson CS, Aldred SF, Lee PK, Tracy RP, Schwartz SM, Rieder M, Liu K, Williams DO, Iribarren C, Lewis CE et al..  2005.  Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels.. American journal of human genetics. 77(1):64-77. Abstract
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Auer PL, Reiner AP, Wang G, Kang HM, Abecasis GR, Altshuler D, Bamshad MJ, Nickerson DA, Tracy RP, Rich SS et al..  2016.  Guidelines for Large-Scale Sequence-Based Complex Trait Association Studies: Lessons Learned from the NHLBI Exome Sequencing Project.. American journal of human genetics. Abstract