Whole-exome imputation of sequence variants identified two novel alleles associated with adult body height in African Americans.

Publication Type:

Journal Article


Human molecular genetics, Volume 23, Issue 24, p.6607-15 (2014)


2014, August 2014, Center-Authored Paper, Public Health Sciences Division, Scientific Imaging Core Facility, Shared Resources, Specimen Processing Core Facility


Adult body height is a quantitative trait for which genome-wide association studies (GWAS) have identified numerous loci, primarily in European populations. These loci, comprising common variants, explain <10% of the phenotypic variance in height. We searched for novel associations between height and common (minor allele frequency, MAF≥5%) or infrequent (0.5%