Waveform analysis-guided treatment versus a standard shock-first protocol for the treatment of out-of-hospital cardiac arrest presenting in ventricular fibrillation: results of an international randomized, controlled trial.

Publication Type:

Journal Article

Source:

Circulation, Volume 128, Issue 9, p.995-1002 (2013)

Keywords:

2013, Adolescent, Adult, Aged, Aged, 80 and over, Algorithms, Cardiopulmonary Resuscitation, Defibrillators, Disease Management, Double-Blind Method, Female, Humans, International Cooperation, Male, Middle Aged, October 2013, Out-of-Hospital Cardiac Arrest, Outcome Assessment (Health Care), Prospective Studies, Public Health Sciences Division, Survival Rate, Treatment Outcome, Ventricular Fibrillation, Young Adult

Abstract:

Ventricular fibrillation (VF) waveform properties have been shown to predict defibrillation success and outcomes among patients treated with immediate defibrillation. We postulated that a waveform analysis algorithm could be used to identify VF unlikely to respond to immediate defibrillation, allowing selective initial treatment with cardiopulmonary resuscitation in an effort to improve overall survival.