Waveform analysis-guided treatment versus a standard shock-first protocol for the treatment of out-of-hospital cardiac arrest presenting in ventricular fibrillation: results of an international randomized, controlled trial.

Publication Type:

Journal Article

Authors:

Freese, John P; Jorgenson, Dawn B; Liu, Ping-Yu; Innes, Jennifer; Matallana, Luis; Nammi, Krishnakant; Donohoe, Rachael T; Whitbread, Mark; Silverman, Robert A; Prezant, David J

Source:

Circulation, Volume 128, Issue 9, p.995-1002 (2013)

Keywords:

2013, Adolescent, Adult, Aged, Aged, 80 and over, Algorithms, Cardiopulmonary Resuscitation, Defibrillators, Disease Management, Double-Blind Method, Female, Humans, International Cooperation, Male, Middle Aged, October 2013, Out-of-Hospital Cardiac Arrest, Outcome Assessment (Health Care), Prospective Studies, Public Health Sciences Division, Survival Rate, Treatment Outcome, Ventricular Fibrillation, Young Adult

Abstract:

Ventricular fibrillation (VF) waveform properties have been shown to predict defibrillation success and outcomes among patients treated with immediate defibrillation. We postulated that a waveform analysis algorithm could be used to identify VF unlikely to respond to immediate defibrillation, allowing selective initial treatment with cardiopulmonary resuscitation in an effort to improve overall survival.