Vitamin E and selenium supplementation and risk of prostate cancer in the Vitamins and lifestyle (VITAL) study cohort.

Publication Type:

Journal Article


Cancer causes & control : CCC, Volume 19, Issue 1, p.75-87 (2008)


2008, Aged, Center-Authored Paper, Cohort Studies, Collaborative Data Services Core Facility, Dietary Supplements, Epidemiology Core Facility, Humans, Male, Middle Aged, Nutrition Assessment Core Facility, Prostatic Neoplasms, Public Health Sciences Division, Risk Factors, SEER Program, Selenium, Shared Resources, Vitamin E, Vitamins


Vitamin E and selenium are promising nutrients for the prevention of prostate cancer, and both are currently being tested in a large randomized trial for prostate cancer. However, results are not expected for at least 6 years. We aimed to investigate the association of vitamin E and selenium supplementation with prostate cancer in the VITamins And Lifestyle (VITAL) study, a cohort study specifically designed to examine supplement use and future cancer risk.