Variation of breast cancer risk among BRCA1/2 carriers.

Publication Type:

Journal Article


JAMA : the journal of the American Medical Association, Volume 299, Issue 2, p.194-201 (2008)


2008, Adult, Aged, Breast Neoplasms, Center-Authored Paper, DNA Mutational Analysis, Epidemiology Core Facility, Female, Genes, BRCA1, Genes, BRCA2, Heterozygote, Humans, Incidence, Matched-Pair Analysis, Middle Aged, Mutation, Public Health Sciences Division, RISK, Shared Resources, Specimen Processing Core Facility


The risk of breast cancer in BRCA1 and BRCA2 mutation carriers has been examined in many studies, but relatively little attention has been paid to the degree to which the risk may vary among carriers.