Validation of genome-wide prostate cancer associations in men of African descent.

Publication Type:

Journal Article

Source:

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Volume 20, Issue 1, p.23-32 (2011)

Keywords:

2011, African Continental Ancestry Group, Case-Control Studies, Center-Authored Paper, Genetic Predisposition to Disease, Genome, Human, Genome-Wide Association Study, Genotype, Great Britain, Humans, Male, Polymorphism, Single Nucleotide, Prostatic Neoplasms, Public Health Sciences Division, Reproducibility of Results, Shared Resources, Specimen Processing Core Facility, United States

Abstract:

Genome-wide association studies (GWAS) have identified numerous prostate cancer susceptibility alleles, but these loci have been identified primarily in men of European descent. There is limited information about the role of these loci in men of African descent.