Use of glucosamine and chondroitin and lung cancer risk in the VITamins And Lifestyle (VITAL) cohort.

Publication Type:

Journal Article

Source:

Cancer causes & control : CCC, Volume 22, Issue 9, p.1333-42 (2011)

Keywords:

2011, Center-Authored Paper, Nutrition Assessment Core Facility, Public Health Sciences Division, September 2011, Shared Resources

Abstract:

Inflammation plays an important role in lung carcinogenesis. Epidemiologic studies have reported inverse associations of non-steroidal anti-inflammatory drug (NSAID) use and lung cancer risk. Previously, we found that ever use of glucosamine and chondroitin, which have anti-inflammatory properties, were inversely associated with lung cancer risk. After an additional year of follow-up, we further examined the association including frequency/duration of use, interaction with factors associated with inflammation, and lung cancer histology.