Treatment of Wilms tumor relapsing after initial treatment with vincristine, actinomycin D, and doxorubicin. A report from the National Wilms Tumor Study Group.

Publication Type:

Journal Article


Pediatric blood & cancer, Volume 50, Issue 2, p.236-41 (2008)


2008, Antineoplastic Combined Chemotherapy Protocols, Carboplatin, Center-Authored Paper, Child, Preschool, Collaborative Data Services Core Facility, Combined Modality Therapy, Dactinomycin, Doxorubicin, Drug Administration Schedule, Etoposide, Female, Humans, Infant, Infant, Newborn, Kidney Neoplasms, Male, Neoplasm Staging, Public Health Sciences Division, RECURRENCE, Shared Resources, Wilms Tumor


We evaluated the use of alternating cycles of cyclophosphamide/etoposide and carboplatin/etoposide in children entered on National Wilms Tumor Study (NWTS)-5 who were diagnosed between August 1, 1995 and May 31, 2002 and who relapsed after chemotherapy with vincristine, actinomycin D, and doxorubicin (VAD) and radiation therapy (DD-4A).