Treatment of nonmuscle invading bladder cancer: do physicians in the United States practice evidence based medicine? The use and economic implications of intravesical chemotherapy after transurethral resection of bladder tumors.

Publication Type:

Journal Article


Cancer, Volume 115, Issue 12, p.2660-70 (2009)


Administration, Intravesical, Algorithms, Antineoplastic Agents, Chemotherapy, Adjuvant, Combined Modality Therapy, Evidence-Based Medicine, Humans, Neoplasm Recurrence, Local, Physician's Practice Patterns, Randomized Controlled Trials as Topic, United States, Urinary Bladder Neoplasms


Phase 3 clinical trials performed primarily outside the US demonstrate that intravesical instillation of chemotherapy immediately after transurethral resection of the bladder (TURB) decreases cancer recurrence rates. The authors sought to determine whether US urologists have adopted this practice, and its potential effect on costs of bladder cancer (BC) care.