Translational control plays a prominent role in the hepatocytic differentiation of HepaRG liver progenitor cells.

Publication Type:

Journal Article


Genome biology, Volume 9, Issue 1, p.R19 (2008)


2008, Cell Death, Cell Differentiation, Cell Line, Cell Proliferation, Energy Metabolism, Gene Expression Regulation, Hepatocytes, Humans, immunity, liver, Protein Biosynthesis, Public Health Sciences Division, RNA, Messenger, Stem Cells


We investigated the molecular events associated with the differentiation of liver progenitor cells into functional and polarized hepatocytes, using human HepaRG cells that display potent hepatocytic differentiation-inducible properties and share some features with liver progenitor cells.