Timing of menarche and first birth in relation to risk of breast cancer in A-bomb survivors.

Publication Type:

Journal Article


Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Volume 19, Issue 7, p.1746-54 (2010)


2010, Age Factors, Breast Neoplasms, Center-Authored Paper, Cohort Studies, Female, Humans, Incidence, Japan, Menarche, Neoplasms, Radiation-Induced, Nuclear Warfare, PREGNANCY, Public Health Sciences Division, Radiation Dosage, Reproductive History, Risk Factors, Survivors


The length of the interval between age at menarche and age at first birth is positively associated with breast cancer risk. We examined the risk of breast cancer in atomic bomb survivors to investigate whether women exposed to radiation between menarche and first birth had a higher risk of radiogenic breast cancer than women exposed at the same age but outside this interval.