Therapeutic opportunities for medulloblastoma come of age.

Publication Type:

Journal Article


Cancer cell, Volume 25, Issue 3, p.267-9 (2014)


2014, April 2014, Clinical Research Division


In this issue of Cancer Cell, Kool and colleagues reveal clear genetically defined subclasses of the sonic hedgehog (SHH) subclass of medulloblastoma. This molecular dissection of the SHH subclass is not simply a cutting-edge advance; the data have profound impact on clinical trial design and decision-making.