Tertiary Gleason pattern 5 in Gleason 7 prostate cancer predicts pathological stage and biochemical recurrence.

Publication Type:

Journal Article

Source:

The Journal of urology, Volume 179, Issue 5, p.1775-9 (2008)

Keywords:

2008, Aged, Human Biology Division, Humans, Male, Middle Aged, Prognosis, Prostate-Specific Antigen, PROSTATECTOMY, Prostatic Neoplasms, Public Health Sciences Division, RECURRENCE

Abstract:

Gleason sum 7 prostate cancers are a heterogeneous group with diverse tumor behaviors and disease outcomes. Tertiary Gleason patterns are reported with increasing frequency, particularly in prostatectomy pathology reports. We studied the pathological and biochemical outcome following radical prostatectomy in men with Gleason sum 7 and tertiary Gleason pattern 5.