Synaptonemal complex formation: where does it start?

Publication Type:

Journal Article


BioEssays : news and reviews in molecular, cellular and developmental biology, Volume 27, Issue 10, p.995-8 (2005)


centromere, Nuclear Proteins, Recombination, Genetic, Saccharomyces cerevisiae, Saccharomyces cerevisiae Proteins, SYNAPTONEMAL COMPLEX


The synaptonemal complex is a prominent, evolutionarily conserved feature of meiotic prophase. The assembly of this structure is closely linked to meiotic recombination. A recent study in budding yeast reveals an unexpected role in centromere pairing for a protein component of the synaptonemal complex, Zip1. These findings have implications for synaptonemal complex formation.