Subsequent malignancies in children treated for Hodgkin's disease: associations with gender and radiation dose.

Publication Type:

Journal Article


International journal of radiation oncology, biology, physics, Volume 72, Issue 1, p.24-33 (2008)


Adolescent, Antineoplastic Combined Chemotherapy Protocols, Breast Neoplasms, Child, Child, Preschool, Combined Modality Therapy, Female, Follow-Up Studies, Hodgkin Disease, Humans, Incidence, Infant, Male, Neoplasms, Radiation-Induced, Neoplasms, Second Primary, Radiotherapy Dosage, RECURRENCE, Sex Factors, Statistics as Topic, Survivors, Thyroid Neoplasms


Subsequent malignant neoplasms (SMNs) are a dominant cause of morbidity and mortality in children treated for Hodgkin's disease (HD). We evaluated select demographic and therapeutic factors associated with SMNs, specifically gender and radiation dose.