Stillbirth and neonatal death in relation to radiation exposure before conception: a retrospective cohort study.

Publication Type:

Journal Article

Authors:

Signorello, Lisa B; Mulvihill, John J; Green, Daniel M; Munro, Heather M; Stovall, Marilyn; Weathers, Rita E; Mertens, Ann C; Whitton, John A; Robison, Leslie L; Boice, John D

Source:

Lancet, Volume 376, Issue 9741, p.624-30 (2010)

Keywords:

2010, Center-Authored Paper, Female, Fertilization, Humans, Infant Mortality, Infant, Newborn, Male, Maternal Exposure, Neoplasms, Ovary, PREGNANCY, Public Health Sciences Division, Radiotherapy Dosage, Stillbirth, Survivors, Testis, Uterus

Abstract:

The reproductive implications of mutagenic treatments given to children with cancer are not clear. By studying the risk of untoward pregnancy outcomes, we indirectly assessed the risk of transmission of germline damage to the offspring of survivors of childhood cancer who were given radiotherapy and chemotherapy.