Statin use and incident frailty in women aged 65 years or older: prospective findings from the Women's Health Initiative Observational Study.

Publication Type:

Journal Article

Source:

The journals of gerontology. Series A, Biological sciences and medical sciences, Volume 63, Issue 4, p.369-75 (2008)

Keywords:

2008, Aged, Aging, Anti-Inflammatory Agents, Center-Authored Paper, Drug Utilization, Fatigue, Female, Frail Elderly, Geriatric Assessment, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Motor Activity, Prevention Center Core Facility, Prospective Studies, Public Health Sciences Division, Shared Resources, Weight Loss, Women's Health

Abstract:

Inflammatory biomarkers have shown consistent associations with disability and frailty in older adults. Statin medications may reduce the incidence the frailty because of their anti-inflammatory effects. This study examines associations between current use, duration, and potency of statin medications and incident frailty in initially nonfrail women 65 years old or older.