Serum vitamin D concentration and prostate cancer risk: a nested case-control study.

Publication Type:

Journal Article


Journal of the National Cancer Institute, Volume 100, Issue 11, p.796-804 (2008)


2008, Aged, Case-Control Studies, Clinical Trials as Topic, Humans, Incidence, Logistic Models, Male, Mass Screening, Middle Aged, Odds Ratio, Prospective Studies, Prostatic Neoplasms, Public Health Sciences Division, Risk Assessment, Risk Factors, United States, Vitamin D


Epidemiological studies have yielded inconsistent associations between vitamin D status and prostate cancer risk, and few studies have evaluated whether the associations vary by disease aggressiveness. We investigated the association between vitamin D status, as determined by serum 25-hydroxyvitamin D [25(OH)D] level, and risk of prostate cancer in a case-control study nested within the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial.